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Gene Expression Data
Assay Details
Assay
Reference: J:195050 Wilson CL, et al., Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mech Dev. 2013 Apr-May;130(4-5):272-89
Assay type: RT-PCR
MGI Accession ID: MGI:6378208
Gene symbol: Adam17
Gene name: a disintegrin and metallopeptidase domain 17
Probe: Adam17-pC, Adam17-pD
Probe preparation: labelled with SYBR green
Results
Image: S2B ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Adam17FL/+ E11.5,12.5 TS19: heart
TS20: heart 		Present 1.5 µg; total RNA involves: C57BL/6 Adam17tm1.1Rain/Adam17+Not Specified
Adam17Fl/deltaEx5 E11.5,12.5 TS19: heart
TS20: heart 		Present 1.5 µg; total RNA involves: C57BL/6 Adam17tm1.1Rain/Adam17tm1.2RainNot Specified
Tie2-Cre/+;Adam17Fl/deltaEx5 E11.5,12.5 TS19: heart
TS20: heart 		Weak (a) 1.5 µg; total RNA B6.Cg-Adam17tm1.1Rain Adam17tm1.2Rain Tg(Tek-cre)12Flv Adam17tm1.1Rain/Adam17tm1.2Rain, Tg(Tek-cre)12Flv/0Not Specified Conditional mutant.
Notes:
(a) There was a partial reduction in expression of Adam17 in the conditional mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory