Gene Expression Data
Assay Details
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Assay
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Reference:
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J:39350
Schneider-Maunoury S, et al., Segmental and neuronal architecture of the hindbrain of Krox-20 mouse mutants. Development. 1997 Mar;124(6):1215-26
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6376297
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Antibody:
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clone 39.4D5
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
7A:
embryonic day 10.5
(more  )
Specimen
7A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Present |
Regionally restricted |
7A
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Expression was detected in motor neurons in the hindbrain. The immunolabeled trigeminal neurons were migrating laterally.
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Specimen
7B:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Present |
Regionally restricted |
7B
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The immunolabeled trigeminal neurons were migrating laterally in the homozgyous mutant, as in control embryos.
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Specimen
not shown:
embryonic day 11.5
(more )
Specimen
not shown:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: hindbrain |
Present |
Regionally restricted |
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Immunolabeled trigeminal neurons completed migration.
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: hindbrain |
Present |
Regionally restricted |
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Immunolabeled trigeminal neurons completed migration in the homozygous mutant as in wild type.
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Specimen
7C:
embryonic day 12.5
(more )
Specimen
7C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: pons |
Present |
Regionally restricted |
7C
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Immunolabeled trigeminal neurons completed migration.
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Specimen
7D:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: pons |
Present |
Regionally restricted |
7D
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Immunolabeled trigeminal neurons completed migration in the homozygous mutant as in wild type, except for a small population of cells which separated from the main part of the Vth nucleus.
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Specimen
7E:
embryonic day 13.5
(more )
Specimen
7E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: pons |
Present |
Regionally restricted |
7E
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The condensation of immunolabeled trigeminal neurons was noted.
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Specimen
7F:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: pons |
Present |
Regionally restricted |
7F
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The condensation of immunolabeled trigeminal neurons was normal in the homozygous mutant embryo.
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Analysis Tools