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Gene Expression Data
Assay Details
Assay
Reference: J:124867 Wrobel CN, et al., Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. Dev Biol. 2007 Sep 15;309(2):285-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6376113
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6A WT: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical subplate Present 6A upper left , 6A lower left
TS25: cerebral cortex Present Regionally restricted 6A upper left , 6A lower left Expression is in layer VI.
Specimen 6A deltaEx3;NesCre: embryonic day 17.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: cerebral cortex Present Widespread 6A lower middle , 6A upper middle Expression is disorganized in this mutant.
Specimen 6A deltaEx3;Nes8Cre: embryonic day 17.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Nes-cre)1Wmz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: cerebral cortex Present Widespread 6A lower right , 6A upper right Expression is disorganized in this mutant.
Specimen 6C: embryonic day 17.5; Ctnnb1tm1Mmt/Ctnnb1+, Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Tbr1; red - Cre reporter.
Structure Level Pattern Image Note
TS25: cerebral cortex Present Widespread 6C Tbr1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory