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Gene Expression Data
Assay Details
Assay
Reference: J:273053 Shih HP, et al., A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361503
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: Anti-Pdx1
Detection system: Alexa Fluor 488
Assay notes: Two antibodies were described, but the one used in this assay was not specified; either MGI:6361200 or MGI:6361201 could have been used.
Results
Specimen S3A: embryonic day 9.5 (more )
Note: Anterior - control. Double labeled: green - Pdx1; red - Sox2 (assay MGI:6361504).
Structure Level Pattern Image Note
TS16: stomach Present S3A'' , S3A
Specimen S3B: embryonic day 9.5 (more )
Note: Posterior - control. Double labeled: green - Pdx1; red - Sox2 (assay MGI:6361504).
Structure Level Pattern Image Note
TS16: pancreas primordium dorsal bud Present S3B'' , S3B
Specimen S3C: embryonic day 9.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Anterior - double mutant. Double labeled: green - Pdx1; red - Sox2 (assay MGI:6361504).
Structure Level Pattern Image Note
TS16: stomach Present S3C , S3C'' The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1 null allele.
Specimen S3D: embryonic day 9.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Posterior - double mutant. Double labeled: green - Pdx1; red - Sox2 (assay MGI:6361504).
Structure Level Pattern Image Note
TS16: pancreas primordium dorsal bud Present S3D , S3D'' The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1 null allele.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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