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Gene Expression Data
Assay Details
Assay
Reference: J:26720 Xuan S, et al., Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron. 1995 Jun;14(6):1141-52
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6324216
Gene symbol: Foxg1
Gene name: forkhead box G1
Reporter: lacZ
Direct Detection
Results
Specimen 2A left: embryonic day 9.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 2A left Expressed in the surface of the telencephalic vesicles. Only minimal differences in the size of the telencephalic vesicles between the mutant and heterozygote.
TS15: olfactory placode Present 2A left Comparable with the heterozygote.
Specimen 2A right: embryonic day 9.5; Foxg1tm1M/Foxg1+ (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 2A right Expressed in the surface of the telencephalic vesicles.
TS15: olfactory placode Present 2A right
Specimen 2B left/D: embryonic day 10.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 2B left Expressed in the surface of the telencephalic vesicles. The growth of the vesicles in the mutant was retarded relative to the heterozygote.
TS17: neural retinal epithelium Present Regionally restricted 2D , 2B left Expressed in the anterior retinal neuroepithelium, which had a wavy appearance.
TS17: nasal epithelium Present 2B left , 2D Fail to grow normally compared with the heterozygote.
TS17: olfactory placode Present 2B left , 2D Fail to grow normally compared with the heterozygote.
Specimen 2B right/E: embryonic day 10.5; Foxg1tm1M/Foxg1+ (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 2B right Expressed in the surface of the telencephalic vesicles.
TS17: neural retinal epithelium Present Regionally restricted 2E , 2B right Expressed in the anterior retinal neuroepithelium.
TS17: nasal epithelium Present 2E , 2B right
TS17: olfactory placode Present 2E , 2B right
Specimen 2C left: embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 2C left Expressed in the surface of the telencephalic vesicles. The growth of the vesicles in the mutant was further retarded relative to the heterozygote.
Specimen 2C right: embryonic day 12.5; Foxg1tm1M/Foxg1+ (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 2C right Expressed in the surface of the telencephalic vesicles.
Specimen 3A: embryonic day 12.5; Foxg1tm1M/Foxg1+ (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3A
TS20: foregut Present 3A
TS20: ganglionic eminence Present 3A
TS20: remnant of Rathke's pouch Present 3A
Specimen 3B: embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: foregut Present 3B
TS20: remnant of Rathke's pouch Present 3B
TS20: telencephalon Present Regionally restricted 3B The ganglionic eminences were not present, only a thin positive neuroepithelium in their place.
TS20: cerebral cortex Present 3B Reduced in size compared with the heterozygote.
Specimen 3C: embryonic day 12.5; Foxg1tm1M/Foxg1+ (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 3C
TS20: ganglionic eminence Present 3C
TS20: nasal epithelium Present 3C
Specimen 3D: embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 3D The ganglionic eminences were not present, only a thin positive neuroepithelium in their place.
TS20: cerebral cortex Present 3D
TS20: nasal epithelium Present 3D Fail to grow normally compared with the heterozygote.
Specimen not shown: embryonic day 8.5-9.0; Foxg1tm1M/Foxg1+ (more )
Structure Level Pattern Image Note
TS13: neural tube Present
Specimen not shown: embryonic day 8.5-9.0; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS13: neural tube Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory