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Gene Expression Data
Assay Details
Assay
Reference: J:264207 Rodgers HM, et al., The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification. Mech Dev. 2018 Jun;151:18-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6317214
Gene symbol: Pdc
Gene name: phosducin
Results
Specimen 8A: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Rax+, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Cre reporter
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted 8A Pdc , 8A Merged Expression was detected along the entire length of the retina at the ventricular surface.

Specimen 8B: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Raxtm1Mjam, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Cre reporter
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted 8B Merged , 8B Pdc In the Rx conditional knockout retina, the central portion of the retina displays expression, but the expression is greatly reduced in the distal portion of the retina.

Specimen 8C: postnatal day 0; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Rax+, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Cre reporter
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted 8C Merged , 8C Pdc Expression was detected along the entire length of the retina at the ventricular surface.

Specimen 8D: postnatal day 0; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Raxtm1Mjam, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Cre reporter
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted 8D Merged , 8D Pdc In the Rx conditional knockout retina, the central portion of the retina displays expression, but the expression is greatly reduced in the distal portion of the retina.

Specimen S1A: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Rax+, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Gngt2 (assay MGI:6317220).
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted S1A Pdc , S1A Merged Expression was detected along the entire length of the retina at the ventricular surface. Strong co-expression was noted with Gngt2.

Specimen S1B: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Raxtm1Mjam, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Gngt2 (assay MGI:6317220).
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted S1B Merged , S1B Pdc In the Rx conditional knockout retina, the central portion of the retina displays co-expression with Gngt2, but the expression is greatly reduced in the distal portion of the retina.

Specimen S1C: postnatal day 0; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Rax+, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Gngt2 (assay MGI:6317220).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S1C Pdc , S1C Merged Expression was detected along the entire length of the retina at the ventricular surface. Strong co-expression was noted with Gngt2.

Specimen S1D: postnatal day 0; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Raxtm1Mjam, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Pdc; green - Gngt2 (assay MGI:6317220).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S1D Merged , S1D Pdc In the Rx conditional knockout retina, the central portion of the retina displays co-expression with Gngt2, but the expression is greatly reduced in the distal portion of the retina.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory