Rax^tm1.1Lwd
Targeted Allele Detail

Summary

• Symbol: Rax^tm1.1Lwd
• Name: retina and anterior neural fold homeobox; targeted mutation 1.1, Mark Lewandoski
• MGI ID: MGI:3576778
• Synonyms: Rx^flox
• Gene: Rax Location: Chr18:66067710-66072160 bp, - strand Genetic Position: Chr18, 39.03 cM
• Alliance: Rax^tm1.1Lwd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97314
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Crossing Rax^tm1Lwd with mice expressing FLP recombinase removed the FRT-flanked neo in intron 1, while exon 2 remained flanked by loxP sites. (J:97314)

Expression

In Mice Carrying this Mutation:

38 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rax Mutation: 16 strains or lines available

References

• Original: J:97314 Voronina VA, et al., Conditional alleles for activation and inactivation of the mouse Rx homeobox gene. Genesis. 2005 Apr;41(4):160-4
• All: 6 reference(s)