Reporter:	lacZ
	Direct Detection

Structure	Level	Pattern	Image	Note
TS15: pancreas primordium dorsal bud	Present	Widespread	3A	Expression throughout dorsal and ventral pancreatic buds.
TS15: pancreas primordium ventral bud	Present	Widespread	3A	Expression throughout dorsal and ventral pancreatic buds.
TS15: foregut-midgut junction	Present	Regionally restricted	3A	Expression in endoderm of presumptive duodenum between dorsal and ventral buds.

Structure	Level	Pattern	Image	Note
TS19: pancreas primordium dorsal bud	Present	Widespread	3B	Expression continues throughout dorsal and ventral buds.
TS19: pancreas primordium ventral bud	Present	Widespread	3B	Expression continues throughout dorsal and ventral buds.
TS19: duodenum	Strong	Graded	3B	Expression in duodenal epithelium is more intense than earlier, declining caudally, and becoming increasingly punctate in the more distal gut.
TS19: stomach	Present	Regionally restricted	3B	Expression in antral stomach with relatively sharp antral/fundic stomach boundary.
TS19: cystic duct	Present		3B
TS19: common bile duct	Present		3B	Relatively sharp liver/common bile duct boundary.

Structure	Level	Pattern	Image	Note
TS24: duodenum	Present		3C	Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.
TS24: pancreas	Present		3C	Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.
TS24: pyloric antrum	Present		3C	Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.

Structure	Level	Pattern	Image	Note
TS24: duodenum	Present		3D	Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.
TS24: pancreas	Present		3D	Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.
TS24: pyloric antrum	Present		3D	Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.
TS24: small intestine	Present	Graded	3D	Expression in gut epithelium tapers off gradually from distal duodenum to ileum.
TS24: jejunum	Present	Punctate	3D	Punctate expression in presumptive jejunum.

Structure	Level	Pattern	Image	Note
TS24: common bile duct	Present			Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.
TS24: cystic duct	Present			Authors report expression is maintained in antral stomach, common bile duct and cystic duct, and in duodenal enterocytes and enteroendocrine cells.
TS24: bile duct	Present	Regionally restricted		Expression in biliary ducts proximal to the common bile duct.

Structure	Level	Pattern	Image	Note
TS26: islets of Langerhans	Present			Just before birth, pancreatic expression becomes restricted mostly to developing islets.
TS26: duodenum epithelium	Present	Regionally restricted		Expression in enterocytes and enteroendocrine cells of the rostral duodenum epithelium.
TS26: gut	Present	Scattered		Expression in scattered epithelial cells in the more distal gut.

Structure	Level	Pattern	Image	Note
TS15: pancreas primordium dorsal bud	Present		3E	Expression in dorsal and ventral buds comparable to that of +/- littermates.
TS15: pancreas primordium ventral bud	Present		3E	Expression in dorsal and ventral buds comparable to that of +/- littermates.
TS15: foregut-midgut junction	Present	Regionally restricted	3E	Expression in presumptive duodenum between dorsal and ventral buds.

Structure	Level	Pattern	Image	Note
TS19: pancreas primordium	Present	Regionally restricted	3F	Pancreatic buds are absent. Expression in dorsal ductule which replaces the dorsal bud.
TS19: stomach	Present	Regionally restricted	3F	Expression in antral stomach. Expression boundary within stomach is the samee as in +/- littermates.
TS19: duodenum	Present	Regionally restricted	3F	Expression in endodermal lining of prospective duodenum
TS19: common bile duct	Present		3F	Expression boundary at the liver is the same as in +/- littermates.

Structure	Level	Pattern	Image	Note
TS24: pyloric antrum	Present		3G
TS24: duodenum	Present		3G	Authors state 'duodenal' gut tube is is simlar length to that of wild-type embryos.

Structure	Level	Pattern	Image	Note
TS24: duodenum	Present		3H
TS24: pancreas	Present		3H
TS24: pyloric antrum	Present		3H
TS24: small intestine	Present	Graded	3H	Expression in gut epithelium tapers off gradually from distal duodenum to ileum.
TS24: jejunum	Present	Punctate	3H	Punctate expression in presumptive jejunum.

Structure	Level	Pattern	Image	Note
TS24: duodenum	Present		4A
TS24: pyloric antrum	Present		4A
TS24: pancreas	Present		4A	Authors report a regular branching pattern in pancreas of +/- embryo.

Structure	Level	Pattern	Image	Note
TS24: pyloric antrum	Present		4B
TS24: pancreatic duct	Present	Regionally restricted	4B	Pancreatic tissues are replaced by small irregularly branched dorsal ductules. Expression in epithelium lining ductules.

Structure	Level	Pattern	Image	Note
TS24: pyloric antrum	Present		4C
TS24: pancreatic duct	Present	Regionally restricted	4C	Pancreatic tissues are replaced by small irregularly branched dorsal ductules. Expression in epithelium lining ductules.

Structure	Level	Pattern	Image	Note
TS15: pancreas primordium	Present	Regionally restricted	5A	Expression in pancreatic buds. No expression in peripheral Gcg-expressing cells.

Structure	Level	Pattern	Image	Note
TS15: pancreas primordium	Present	Regionally restricted	5B	Expression in pancreatic buds. No expression in peripheral Gcg-expressing cells.

Structure	Level	Pattern	Image	Note
TS19: pancreas primordium dorsal bud	Present		5C	Expression in pancreatic buds. No expression in peripheral Gcg-expressing cells.

Structure	Level	Pattern	Image	Note
TS19: pancreas primordium	Present	Regionally restricted	5D	Dorsal pancreatic bud is replaced by dorsal ductule. No expression in peripheral Gcg-expressing cells.

Structure	Level	Pattern	Image	Note
TS24: islets of Langerhans	Present		5E	Expression in budding islets.

Structure	Level	Pattern	Image	Note
TS24: islets of Langerhans	Present		5F	Expression in budding islets.

Structure	Level	Pattern	Image	Note
TS24: islets of Langerhans	Present		5G	Expression in budding islets.

Structure	Level	Pattern	Image	Note
TS24: pancreas epithelium	Present	Regionally restricted	5I	Expression in epithelium of dorsal ductules.

Structure	Level	Pattern	Image	Note
TS24: pancreas epithelium	Present	Regionally restricted	5J	Expression in epithelium of dorsal ductules.

Structure	Level	Pattern	Image	Note
TS24: pancreas epithelium	Present	Regionally restricted	5K	Expression in epithelium of dorsal ductules.