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Gene Expression Data
Assay Details
Assay
Reference: J:231835 Nishii K, et al., Connexin45 contributes to global cardiovascular development by establishing myocardial impulse propagation. Mech Dev. 2016 May;140:41-52
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6315224
Gene symbol: Gjc1
Gene name: gap junction protein, gamma 1
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 9.5; Gjc1tm2Kni/Gjc1+, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1A
Specimen 1B: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1B
Specimen 1C: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: heart endothelium Present 1C
Specimen 1D: embryonic day 9.5; Gjc1tm1.1Kni/Gjc1tm1.1Kni (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1D
Specimen 1F: embryonic day 9.5; Gjc1tm1.1Kni/Gjc1+ (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Uniform 1F
Specimen 1G: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Non-Uniform 1G Many X-gal-negative patches were seen.
Specimen 1H: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Non-Uniform 1H Many X-gal-negative patches were seen.
Specimen 1I: embryonic day 9.5; Gjc1tm2Kni/Gjc1+, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1I
Specimen 1J: embryonic day 9.5; Gjc1tm2Kni/Gjc1+, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: heart endothelium Present 1J
Specimen 1K: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: heart endothelium Present 1K
Specimen 1L: embryonic day 9.5; Gjc1tm1.1Kni/Gjc1tm1.1Kni (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1L
Specimen 1M: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1M
Specimen 1N: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1N
Specimen 1O: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1O
Specimen 1P: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1P
TS15: heart endothelium Present 1P
Specimen 2A Tie2-Cre; Cx45flox/flox: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: endocardial cushion Present Regionally restricted 2A Tie2-Cre; Cx45flox/flox Emerging cushion mesenchymal cells were labeled.
Specimen 2A Cx45-/- left: embryonic day 9.5; Gjc1tm1.1Kni/Gjc1tm1.1Kni (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 2A Cx45-/- left
Specimen 2A Cx45-/- right: embryonic day 9.5; Gjc1tm1.1Kni/Gjc1tm1.1Kni (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 2A Cx45-/- right
Specimen 2A CA-Cre; Cx45+/flox: embryonic day 9.5; Gjc1tm2Kni/Gjc1+, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Non-Uniform 2A CA-Cre; Cx45+/flox Patchy X-gal-negative areas were present in the myocardium.
Specimen 2A CA-Cre; Cx45flox/flox left: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Non-Uniform 2A CA-Cre; Cx45flox/flox left Patchy X-gal-negative areas were present in the myocardium.
Specimen 2A CA-Cre Cx45flox/flox right: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Non-Uniform 2A CA-Cre Cx45flox/flox right Patchy X-gal-negative areas were present in the myocardium.
Specimen 2A Ca-Cre; Tie2-Cre; Cx45flox/flox: embryonic day 9.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Non-Uniform 2A Ca-Cre; Tie2-Cre; Cx45flox/flox Patchy X-gal-negative areas were present in the myocardium.
TS15: endocardial cushion Present Single cells 2A Ca-Cre; Tie2-Cre; Cx45flox/flox A few X-gal-positive cushion mesenchymal cells were noted.
Specimen 2C Cx45+/-: embryonic day 10.5; Gjc1tm1.1Kni/Gjc1+ (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 2C Cx45+/-
Specimen 2C CA-Cre; Cx45flox/flox left: embryonic day 10.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 2C CA-Cre; Cx45flox/flox left
TS17: outflow tract endocardial cushion Present 2C CA-Cre; Cx45flox/flox left
Specimen 2C CA-Cre; Cx45flox/flox right: embryonic day 10.5; Gjc1tm2Kni/Gjc1tm2Kni, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 2C CA-Cre; Cx45flox/flox right
Specimen 2C CA-Cre; Cx45+/flox: embryonic day 10.5; Gjc1tm2Kni/Gjc1+, Tg(ACTC1-cre)1Miwa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 2C CA-Cre; Cx45+/flox
Specimen 2D Tie2-Cre; Cx45flox/flox left: embryonic day 11.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: atrioventricular endocardial cushion Present 2D Tie2-Cre; Cx45flox/flox left
Specimen 2D Tie2-Cre; Cx45flox/flox eminence 1: embryonic day 11.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: atrioventricular endocardial cushion Present 2D Tie2-Cre; Cx45flox/flox eminence 1
Specimen 2D Tie2-Cre; Cx45flox/flox eminence 2: embryonic day 11.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: atrioventricular endocardial cushion Present 2D Tie2-Cre; Cx45flox/flox eminence 2
Specimen 2D Tie2-Cre; Cx45flox/flox eminence 3: embryonic day 11.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: atrioventricular endocardial cushion Present 2D Tie2-Cre; Cx45flox/flox eminence 3
Specimen 2D Tie2-Cre; Cx45flox/flox eminence 4: embryonic day 11.5; Gjc1tm2Kni/Gjc1tm2Kni (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: atrioventricular endocardial cushion Present 2D Tie2-Cre; Cx45flox/flox eminence 4
Specimen S3 +/-: embryonic day 10.5; Gjc1tm1.1Kni/Gjc1+ (more )
Structure Level Pattern Image Note
TS17: chorionic plate Present S3_+/-
TS17: labyrinthine zone Absent S3_+/-
Specimen S3 -/-: embryonic day 10.5; Gjc1tm1.1Kni/Gjc1tm1.1Kni (more )
Structure Level Pattern Image Note
TS17: chorionic plate Present S3_-/-
TS17: labyrinthine zone Absent S3_-/-
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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