Gene Expression Image Detail

Reference

Figure

ID

J:231835 Nishii K, et al., Mech Dev. 2016 May;140:41-52

2

MGI:6314834

Image

Caption

(A) Sagittal sections of the atrioventricular canal region at E9.5 with X-gal staining and hematoxylin counterstaining. Endocardial cushion (arrows). Cardiac jelly (asterisks). (C) Sagittal X-gal-stained sections of the heart in Cx45+/- and CA-Cre; Cx45^flox/flox, and coronal sections in CA-Cre; Cx45^+/flox and CA-Cre; Cx45^flox/flox heart at E10.5. (D) Sagittal X-gal-stained sections of the heart at E11.5. Magnified views of upper and lower eminences of the atrioventricular cushion from two independent Tie2-Cre; Cx45^flox/flox embryos are shown. a, atrium; cor, bulbus cordis; e, endocardial endothelium; m, myocardium of the atrioventricular canal; o, outflow tract; v, ventricle. Scale bars = 100 um.

Copyright

Reprinted with permission from Elsevier from 10.1016/j.mod.2016.02.003 Mech Dev 140: 41-52, Nishii K; Seki A; Kumai M; Morimoto S; Miwa T; Hagiwara N; Shibata Y; Kobayashi Y, Connexin45 contributes to global cardiovascular development by establishing myocardial impulse propagation. Copyright 2016.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A Tie2-Cre; Cx45^flox/flox	MGI:6315224 (Gjc1)
A Cx45^-/- left	MGI:6315224 (Gjc1)
A Cx45^-/- right	MGI:6315224 (Gjc1)
A CA-Cre; Cx45^+/flox	MGI:6315224 (Gjc1)
A CA-Cre; Cx45^flox/flox left	MGI:6315224 (Gjc1)
A CA-Cre Cx45^flox/flox right	MGI:6315224 (Gjc1)
A Ca-Cre; Tie2-Cre; Cx45^flox/flox	MGI:6315224 (Gjc1)
C Cx45^+/-	MGI:6315224 (Gjc1)
C CA-Cre; Cx45^flox/flox left	MGI:6315224 (Gjc1)
C CA-Cre; Cx45^+/flox	MGI:6315224 (Gjc1)
C CA-Cre; Cx45^flox/flox right	MGI:6315224 (Gjc1)
D Tie2-Cre; Cx45^flox/flox left	MGI:6315224 (Gjc1)
D Tie2-Cre; Cx45^flox/flox eminence 3	MGI:6315224 (Gjc1)
D Tie2-Cre; Cx45^flox/flox eminence 4	MGI:6315224 (Gjc1)
D Tie2-Cre; Cx45^flox/flox eminence 1	MGI:6315224 (Gjc1)
D Tie2-Cre; Cx45^flox/flox eminence 2	MGI:6315224 (Gjc1)