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Gene Expression Data
Assay Details
Assay
Reference: J:200936 Wright-Jin EC, et al., Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function. Dev Biol. 2013 Sep 1;381(1):28-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6297046
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tuj1
Results
Specimen 3a SI WT: postnatal adult (more )
Structure Level Pattern Image Note
TS28: duodenum Present 3a SI WT
TS28: myenteric nerve plexus Present 3a SI WT

Specimen 3a SI R1koR2hetR3het: postnatal adult; Aldh1a1tm1Gdu/Aldh1a1tm1Gdu, Aldh1a2tm1Gdu/Aldh1a2+, Aldh1a3tm1Gdu/Aldh1a3+ (more )
Structure Level Pattern Image Note
TS28: duodenum Present 3a S1 R1koR2hetR3het Authors report neuronal fiber density equal to wild type in the small intestine.
TS28: myenteric nerve plexus Present 3a S1 R1koR2hetR3het Authors report neuronal fiber density equal to wild type in the small intestine.

Specimen 3a CO WT: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon Present 3a CO WT
TS28: myenteric nerve plexus Present 3a CO WT

Specimen 3a CO R1koR2hetR3het: postnatal adult; Aldh1a1tm1Gdu/Aldh1a1tm1Gdu, Aldh1a2tm1Gdu/Aldh1a2+, Aldh1a3tm1Gdu/Aldh1a3+ (more )
Structure Level Pattern Image Note
TS28: colon Present 3a CO R1koR2hetR3het Authors report neuronal fiber density equal to wild type in the colon.
TS28: myenteric nerve plexus Present 3a CO R1koR2hetR3het Authors report neuronal fiber density equal to wild type in the colon.

Specimen 6a WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: enteric nervous system Present 6a WT

Specimen 6a R1wtR2hetR3wt: embryonic day 13.5; Aldh1a2tm1Gdu/Aldh1a2+ (more )
Structure Level Pattern Image Note
TS21: enteric nervous system Present 6a R1wtR2hetR3wt

Specimen 6a R1koR2hetR3wt: embryonic day 13.5; Aldh1a1tm1Gdu/Aldh1a1tm1Gdu, Aldh1a2tm1Gdu/Aldh1a2+ (more )
Structure Level Pattern Image Note
TS21: enteric nervous system Present 6a R1koR2hetR3wt

Specimen 6a R1koR2hetR3het: embryonic day 13.5; Aldh1a1tm1Gdu/Aldh1a1tm1Gdu, Aldh1a2tm1Gdu/Aldh1a2+, Aldh1a3tm1Gdu/Aldh1a3+ (more )
Structure Level Pattern Image Note
TS21: enteric nervous system Present Regionally restricted 6a R1koR2hetR3het Authors report in increased enteric neuron colonization in the colon, based on position of most distal cells, compared to wild type.

Specimen 6a R1koR2hetR3ko: embryonic day 13.5; Aldh1a1tm1Gdu/Aldh1a1tm1Gdu, Aldh1a2tm1Gdu/Aldh1a2+, Aldh1a3tm1Gdu/Aldh1a3tm1Gdu (more )
Structure Level Pattern Image Note
TS21: enteric nervous system Present Regionally restricted 6a R1koR2hetR3ko Authors report in increased enteric neuron colonization in the colon, based on position of most distal cells, compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory