About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6188917
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH (sheep; NB300-110)
Detection system: Secondary antibody
Assay notes: The authors used two antibodies to TH but did not distinguish which data was derived from which; it is likely MGI:6159043 was used to obtain at least some of these data.
Results
Specimen Table 3A/B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: enteric nervous system Present Co-expression analysis was done (in the stomach) with a number of transcription factors. The table details which were co-expressed, partially co-expressed or not co-expressed.
Specimen 3C - EBF1: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Ebf1 (assay MGI:6164656).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C EBF1 Co-expression with Ebf1 was observed in the stomach.
Specimen 3C - MEIS2: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Meis2 (assay MGI:6164666).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C MEIS2 Co-expression with Meis2 was observed in the stomach.
Specimen 3C - ETV1: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Etv1 (assay MGI:6164657).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C ETV1 Co-expression with Etv1 was observed in the stomach.
Specimen 3C - SATB1: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Satb1 (assay MGI:6164709).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C SATB1 Co-expression with Satb1 was observed in the stomach.
Specimen 3C - KLF7: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Klf7 (assay MGI:6164664).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C KLF7 Co-expression with Klf7 was observed in the stomach.
Specimen 3C - SOX6: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Sox6 (assay MGI:6188909).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C SOX6 Co-expression with Sox6 was observed in the stomach.
Specimen 4B: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Sox6 (assay MGI:6188909).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4B TH Expression is present in neurons.
Specimen 4D - center: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Npy (assay MGI:6189075).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4D TH/NPY Double staining shows no co-expression with NPY.
Specimen 4D - right: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Calb1 (assay MGI:6189071).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4D TH/CALB1 Double staining shows no co-expression with Calb1.
Specimen 4F: embryonic day 18.5 (more )
Note: Littermates were used as controls.
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4F TH Expression is present in gastric neurons.
Specimen 4G: embryonic day 18.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4G TH Expression is present in gastric neurons, but it is reduced 70% in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory