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Gene Expression Data
Assay Details
Assay
Reference: J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6188917
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH (sheep; NB300-110)
Detection system: Secondary antibody
Assay notes: The authors used two antibodies to TH but did not distinguish which data was derived from which; it is likely MGI:6159043 was used to obtain at least some of these data.
Results
Specimen Table 3A/B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: enteric nervous system Present Co-expression analysis was done (in the stomach) with a number of transcription factors. The table details which were co-expressed, partially co-expressed or not co-expressed.
Specimen 3C - EBF1: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Ebf1 (assay MGI:6164656).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C EBF1 Co-expression with Ebf1 was observed in the stomach.
Specimen 3C - MEIS2: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Meis2 (assay MGI:6164666).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C MEIS2 Co-expression with Meis2 was observed in the stomach.
Specimen 3C - ETV1: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Etv1 (assay MGI:6164657).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C ETV1 Co-expression with Etv1 was observed in the stomach.
Specimen 3C - SATB1: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Satb1 (assay MGI:6164709).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C SATB1 Co-expression with Satb1 was observed in the stomach.
Specimen 3C - KLF7: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Klf7 (assay MGI:6164664).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C KLF7 Co-expression with Klf7 was observed in the stomach.
Specimen 3C - SOX6: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Sox6 (assay MGI:6188909).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 3C SOX6 Co-expression with Sox6 was observed in the stomach.
Specimen 4B: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Sox6 (assay MGI:6188909).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4B TH Expression is present in neurons.
Specimen 4D - center: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Npy (assay MGI:6189075).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4D TH/NPY Double staining shows no co-expression with NPY.
Specimen 4D - right: embryonic day 18.5 (more )
Note: Double labeled: green - Th; red - Calb1 (assay MGI:6189071).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4D TH/CALB1 Double staining shows no co-expression with Calb1.
Specimen 4F: embryonic day 18.5 (more )
Note: Littermates were used as controls.
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4F TH Expression is present in gastric neurons.
Specimen 4G: embryonic day 18.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4G TH Expression is present in gastric neurons, but it is reduced 70% in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory