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Gene Expression Data
Assay Details
Assay
Reference: J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6189075
Gene symbol: Npy
Gene name: neuropeptide Y
Antibody: anti-NPY (ab6173)
Detection system: Secondary antibody
Assay notes: The authors used two antibodies to NPY but did not distinguish which data was derived from which; it is likely MGI:6159145 was used to obtain at least some of these data.
Results
Specimen Table 3A/B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: enteric nervous system Present Co-expression analysis was done (in the stomach) with a number of transcription factors. The table details which were co-expressed, partially co-expressed or not co-expressed.

Specimen 4B: embryonic day 18.5 (more )
Note: Double labeled: green - Npy; red - Sox6 (assay MGI:6188909).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4B NPY Expression is present in neurons.

Specimen 4D - left: embryonic day 18.5 (more )
Note: Double labeled: green - Npy; red - Calb1 (assay MGI:6189071).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4D NPY/CALB1 Double staining shows 95% of NPY-positive neurons co-express Calb1.

Specimen 4D - center: embryonic day 18.5 (more )
Note: Double labeled: red - Npy; green - Th (assay MGI:6188917).
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4D TH/NPY Double staining shows no co-expression with TH.

Specimen 4F: embryonic day 18.5 (more )
Note: Littermates were used as controls.
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4F NPY Expression is present in gastric neurons.

Specimen 4G: embryonic day 18.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Sox6tm2.1Vlf/Sox6tm2.1Vlf (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: enteric nervous system Present 4G NPY Expression is present in gastric neurons; similar numbers are seen in mutant compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory