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Gene Expression Data
Assay Details
Assay
Reference: J:101265 Kuijper S, et al., Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh. Dev Biol. 2005 Sep 15;285(2):533-44
Assay type: RNA in situ
MGI Accession ID: MGI:6149011
Gene symbol: Fgf4
Gene name: fibroblast growth factor 4
Probe: Fgf-4 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 10.5 (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: forelimb bud Present 2A
Specimen 2B: embryonic day 10.5; Alx4Lst-2J/Alx4lst-J (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 2B
TS17: forelimb bud apical ectodermal ridge Present Regionally restricted 2B Authors report ectopic expression of Fgf4 in the anterior part of the apical ectodermal ridge.
Specimen 2C: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 2C Low levels of Fgf4 in posterior part of limb bud.
Specimen 2C': embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 2C' Low levels of Fgf4 in posterior part of limb bud.
Specimen 2D: embryonic day 10.5; Alx4lst-J/Alx4lst-J, Shhtm1Chg/Shhtm1Chg (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 2D Expression reduced posteriorly in limb bud.
Specimen 2D': embryonic day 10.5; Alx4lst-J/Alx4lst-J, Shhtm1Chg/Shhtm1Chg (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 2D' Expression reduced posteriorly in limb bud. Authors report ectopic anterior spot of Fgf4 expression.
Specimen 2E: embryonic day 10.5 (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: hindlimb bud Present 2E
Specimen 2F: embryonic day 10.5; Alx4Lst-2J/Alx4lst-J (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted 2F Authors report ectopic Fgf4 expression
TS17: hindlimb bud apical ectodermal ridge Present Widespread 2F Fgf4 expression extended throughout the apical ectodermal ridge.
Specimen 2G: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: hindlimb bud Present 2G
Specimen 2H: embryonic day 10.5; Alx4lst-J/Alx4lst-J, Shhtm1Chg/Shhtm1Chg (more )
Note: Also stained for Grem1 (assay MGI:6149012).
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted 2H Authors report ectopic Fgf4 expression
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory