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Htd2 Gene Detail
Summary
  • Symbol
    Htd2
  • Name
    hydroxyacyl-thioester dehydratase type 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:5827763
    NCBI Gene: 109729085
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:14377937-14389436 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    555 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5827763
 protein coding gene Chr14:14377937-14389436 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 109729085 NCBI Gene Model | MGI Sequence Detail 11500 C57BL/6J ±  kb
transcript NM_001348727 RefSeq | MGI Sequence Detail 2446 ZRU/MplStud  
polypeptide NP_001335656 RefSeq | MGI Sequence Detail 158 ZRU/MplStud  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR029069 HotDog domain superfamily
    IPR002539 MaoC-like dehydratase domain
    IPR050965 UPF0336/Enoyl-CoA hydratase-related
References
more
  • Summaries
    All 6
  • Earliest
    J:309783 Zeng M, et al., Htd2 deficiency-associated suppression of alpha-lipoic acid production provokes mitochondrial dysfunction and insulin resistance in adipocytes. Redox Biol. 2021 May;41:101948
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory