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Gene Expression Data
Assay Details
Assay
Reference: J:79223 King T, et al., Expression of Peg1 (Mest) in the developing mouse heart: Involvement in trabeculation. Dev Dyn. 2002 Oct;225(2):212-5
Assay type: RNA in situ
MGI Accession ID: MGI:5824288
Gene symbol: Mest
Gene name: mesoderm specific transcript
Results
Specimen 1A,A': embryonic day 9.0 (more )
Note: 12 somites.
Structure Level Pattern Image Note
TS13: primitive ventricle cardiac muscle Present 1A Expression was concentrated in the ventricular myocardium and strongest in the trabeculae.
TS13: primitive ventricle endocardial tube Present 1A
TS13: common atrial chamber cardiac muscle Absent 1A , 1A'
TS13: atrioventricular canal cardiac muscle Absent 1A' , 1A Expression was absent from myocardium of the atrioventricular junction.
TS13: common atrial chamber endocardial tube Present 1A , 1A'
TS13: outflow tract Absent 1A

Specimen 1B: embryonic day 10.0 (more )
Note: 14 somites.
Structure Level Pattern Image Note
TS17: primitive ventricle cardiac muscle Present 1B Expression was concentrated in the ventricular myocardium and strongest in the trabeculae.
TS17: primitive ventricle endocardial lining Present 1B
TS17: outflow tract cardiac muscle Absent 1B
TS17: common atrial chamber cardiac muscle Present Regionally restricted 1B Expression starts to appear in the myocardium of the future right atrial appendage but remains absent in the left appendage.
TS17: atrioventricular canal cardiac muscle Absent 1B Expression is absent from the myocardial component of the atrioventricular junction.

Specimen 1C: embryonic day 10.0 (more )
Note: 17 somites.
Structure Level Pattern Image Note
TS17: primitive ventricle cardiac muscle Present 1C Expression was concentrated in the ventricular myocardium and strongest in the trabeculae.
TS17: primitive ventricle endocardial lining Present 1C
TS17: outflow tract cardiac muscle Absent 1C
TS17: common atrial chamber cardiac muscle Present Regionally restricted 1C Expression starts to appear in the myocardium of the future right atrial appendage but remains absent in the left appendage.
TS17: atrioventricular canal cardiac muscle Absent 1C Expression is absent from the myocardial component of the atrioventricular junction.

Specimen 1D: embryonic day 10.0 (more )
Note: 15 somites.
Structure Level Pattern Image Note
TS17: heart Present 1D

Specimen 1E: embryonic day 11.0 (more )
Note: 28 somites. E-G: serial sections caudal to cranial.
Structure Level Pattern Image Note
TS19: atrium cardiac muscle Present Non-Uniform 1E Expression was found in the myocardium of both the atrial appendages being, however, significantly stronger on the right than on the left.
TS19: endocardial lining Present Widespread 1E Endocardial cells express throughout the heart.
TS19: visceral pericardium Present 1E
TS19: atrioventricular endocardial cushion Absent 1E

Specimen 1F: embryonic day 11.0 (more )
Note: 28 somites. E-G: serial sections caudal to cranial.
Structure Level Pattern Image Note
TS19: endocardial lining Present Widespread 1F Endocardial cells express throughout the heart.
TS19: interventricular septum cardiac muscle Absent 1F Expression was not detected in the compact myocardium of the developing interventricular septum.
TS19: atrioventricular endocardial cushion Absent 1F

Specimen 1G: embryonic day 11.0 (more )
Note: 28 somites. E-G: serial sections caudal to cranial.
Structure Level Pattern Image Note
TS19: endocardial lining Present Widespread 1G Endocardial cells express throughout the heart.
TS19: interventricular septum cardiac muscle Absent 1G Expression was not detected in the compact myocardium of the developing interventricular septum.
TS19: outflow tract cardiac muscle Absent 1G

Specimen 1H: embryonic day 11.0 (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS19: atrium cardiac muscle Present Non-Uniform 1H Expression was found in the myocardium of both the atrial appendages being, however, significantly stronger on the right than on the left.
TS19: trabecular myocardium Present Regionally restricted 1H There is a sharp boundary of expression between the future right ventricle and the outflow tract, corresponding to the cranial extent of trabeculation.

Specimen 1I: embryonic day 12.0 (more )
Note: 44 somites. I-K: serial sections caudal to cranial.
Structure Level Pattern Image Note
TS20: ventricle cardiac muscle Present Regionally restricted 1I Expression in the ventricular compact outer myocardium is either absent or much lower than in the trabeculae.
TS20: atrioventricular endocardial cushion Absent 1I
TS20: interventricular septum cardiac muscle Absent 1I
TS20: outflow tract cardiac muscle Absent 1I
TS20: visceral pericardium Present 1I

Specimen 1J: embryonic day 12.0 (more )
Note: 44 somites. I-K: serial sections caudal to cranial.
Structure Level Pattern Image Note
TS20: trabecular myocardium Present Regionally restricted 1J Expression was increased in the atrial trabeculae, particularly in the right.

Specimen 1K: embryonic day 12.0 (more )
Note: 44 somites. I-K: serial sections caudal to cranial.
Structure Level Pattern Image Note
TS20: trabecular myocardium Present Non-Uniform 1K There is a sharp boundary of expression between the future right ventricle and the outflow tract, corresponding to the cranial extent of trabeculation. Expression was increased in the atrial trabeculae, particularly in the right.

Specimen 1L: embryonic day 12.0 (more )
Note: 38 somites.
Structure Level Pattern Image Note
TS20: trabecular myocardium Present Non-Uniform 1L There is a sharp boundary of expression between the future right ventricle and the outflow tract, corresponding to the cranial extent of trabeculation.

Specimen 1M: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: compact myocardium Present Regionally restricted 1M Expression was detected in atria as well as ventricles.
TS22: trabecular myocardium Present Regionally restricted 1M Expression was detected in atria as well as ventricles.

Specimen 1N: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: compact myocardium Present Regionally restricted 1N Expression was detected in atria as well as ventricles.
TS24: trabecular myocardium Present Regionally restricted 1N Expression was detected in atria as well as ventricles.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: heart Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory