Pdx1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:229891 Xuan S, et al., GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development. 2016 Mar 1;143(5):780-6
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5796003
Gene symbol:	Pdx1
Gene name:	pancreatic and duodenal homeobox 1

Antibody:	anti-Pdx1 (07-696)
Detection system:	Secondary antibody

Results

2B ©

2D ©

2D' ©

Specimen 2B: embryonic day 10.5 (more

)
Note: Double labeled: blue - Pdx1; green - Sox2 (assay MGI:5796005).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium dorsal bud	Present		2D' , 2B , 2D

2F ©

2H ©

2H' ©

Specimen 2F: embryonic day 10.5; Gata4^tm1.1Sad/Gata4^tm1.1Sad, Gata6^tm2.1Sad/Gata6^tm2.1Sad, Tg(Pdx1-cre)6Tuv/0 (more

)
Note: Conditional mutant. Double labeled: blue - Pdx1; green - Sox2 (assay MGI:5796005).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium dorsal bud	Absent		2F , 2H , 2H'

2J ©

2L ©

2L' ©

Specimen 2J: embryonic day 9.5 (more

)
Note: Double labeled: blue - Pdx1; green - Cdx2 (assay MGI:5796006).

Structure	Level	Pattern	Image	Note
TS15: foregut	Present	Regionally restricted	2J , 2L , 2L'	Expression is in the foregut endoderm.

2N ©

2P ©

2P' ©

2P'' ©

Specimen 2N: embryonic day 9.5; Gata4^tm1.1Sad/Gata4^tm1.1Sad, Gata6^tm2.1Sad/Gata6^tm2.1Sad, Tg(Pdx1-cre)6Tuv/0 (more

)
Note: Conditional mutant. Double labeled: blue - Pdx1; green - Cdx2 (assay MGI:5796006).

Structure	Level	Pattern	Image	Note
TS15: foregut	Present	Regionally restricted	2P'' , 2P , 2N , 2P'	A few pancreatic limeage cells have lost expression.

2S ©

2U ©

2U' ©

Specimen 2S: embryonic day 10.5 (more

)
Note: Double labeled: blue - Pdx1; green - Cdx2 (assay MGI:5796006).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium dorsal bud	Present		2U , 2S , 2U'

2W ©

2Y ©

2Y' ©

Specimen 2W: embryonic day 10.5; Gata4^tm1.1Sad/Gata4^tm1.1Sad, Gata6^tm2.1Sad/Gata6^tm2.1Sad, Tg(Pdx1-cre)6Tuv/0 (more

)
Note: Conditional mutant. Double labeled: blue - Pdx1; green - Cdx2 (assay MGI:5796006).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium	Present	Regionally restricted	2W , 2Y' , 2Y	An increasing number of pancreatic limeage cells have lost expression.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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