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Gene Expression Data
Assay Details
Assay
Reference: J:148533 Saito K, et al., Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8350-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5661037
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tubulin beta 3 (clone TUJ1, MMS-435P/801202)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A telencephalon E11.5 control: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 2A telencephalon E11.5 TUJ1 control , 2A telencephalon E11.5 control merge

Specimen 2A telencephalon E11.5 SQS-cKO: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 2A telencephalon E11.5 TUJ1 SQS-cKO , 2A telencephalon E11.5 SQS-cKO merge

Specimen 2A telencephalon E12.5 control: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 2A telencephalon E12.5 TUJ1 control , 2A telencephalon E12.5 control merge

Specimen 2A telencephalon E12.5 SQS-cKO: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 2A telencephalon E12.5 TUJ1 SQS-cKO , 2A telencephalon E12.5 SQS-cKO merge

Specimen 2A telencephalon E13.5 control: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 2A telencephalon E13.5 TUJ1 control , 2A telencephalon E13.5 control merge

Specimen 2A telencephalon E13.5 SQS-cKO: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 2A telencephalon E13.5 SQS-cKO merge , 2A telencephalon E13.5 TUJ1 SQS-cKO

Specimen 2A telencephalon E15.5 control: embryonic day 15.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Regionally restricted 2A telencephalon E15.5 control merge , 2A telencephalon E15.5 TUJ1 control

Specimen 2A telencephalon E15.5 SQS-cKO: embryonic day 15.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Regionally restricted 2A telencephalon E15.5 SQS-cKO merge , 2A telencephalon E15.5 TUJ1 SQS-cKO Authors report a reduction in radial thickness of neuronal layer compared with control embryos.

Specimen 2A diencephalon E11.5 control: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 2A diencephalon E11.5 control merge , 2A diencephalon E11.5 TUJ1 control

Specimen 2A diencephalon E11.5 SQS-cKO: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 2A diencephalon E11.5 SQS-cKO merge , 2A diencephalon E11.5 TUJ1 SQS-cKO

Specimen 2A diencephalon E12.5 control: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 2A diencephalon E12.5 control merge , 2A diencephalon E12.5 TUJ1 control

Specimen 2A diencephalon E12.5 SQS-cKO: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 2A diencephalon E12.5 TUJ1 SQS-cKO , 2A diencephalon E12.5 SQS-cKO merge

Specimen 2A diencephalon E13.5 control: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 2A diencephalon E13.5 control merge , 2A diencephalon E13.5 TUJ1 control

Specimen 2A diencephalon E13.5 SQS-cKO: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 2A diencephalon E13.5 TUJ1 SQS-cKO , 2A diencephalon E13.5 SQS-cKO merge Authors report a reduction in radial thickness of neuronal layer compared with control embryos.


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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory