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Gene Expression Data
Assay Details
Assay
Reference: J:74094 Nagahama H, et al., Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development. Anat Embryol (Berl). 2001 Feb;203(2):77-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5648496
Gene symbol: Cdkn1b
Gene name: cyclin dependent kinase inhibitor 1B
Antibody: Anti-p27 Kip1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metanephros visceral epithelium Present 1A

Specimen 1C: embryonic day 14.5; Cdkn1btm1Kin/Cdkn1btm1Kin (more )
Structure Level Pattern Image Note
TS22: metanephros visceral epithelium Absent 1C

Specimen 1E: embryonic day 14.5; Cdkn1ctm1Kat/Cdkn1ctm1Kat (more )
Structure Level Pattern Image Note
TS22: metanephros visceral epithelium Present 1E

Specimen 1G: embryonic day 14.5; Cdkn1btm1Kin/Cdkn1btm1Kin, Cdkn1ctm1Kat/Cdkn1ctm1Kat (more )
Structure Level Pattern Image Note
TS22: metanephros visceral epithelium Absent 1G

Specimen 2A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ovary Present Regionally restricted 2A Expression was in granulosa cells, as well as interstitial cells.
TS28: ovary follicle cell Present 2A

Specimen 2C: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 2C
TS28: Sertoli cell Sertoli cell Present 2C

Specimen 2E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thymus cortex Present 2E
TS28: thymus medullary core Present 2E

Specimen 2G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine Absent 2G

Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 3A Expression was detected in the developing retina (retinoblasts and pigment epithelium).

Specimen 3C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens equatorial epithelium Present 3C Coexpression with p57 (Cdkn1c) was noted.

Specimen 3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: endocardial lining Present 3E Coexpression with p57 (Cdkn1c) was noted.
TS17: cardiac muscle tissue Present 3E

Specimen 4A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adrenal medulla Present 4A
TS28: adrenal cortex Absent 4A

Specimen 4C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted 4C Expression was detected on the lateral side of the organ of Corti.

Specimen 6 E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted Expression was detected mostly in the intermediate zone where postmitotic neurons migrate.
TS15: cardiac muscle tissue Present
TS15: endocardial lining Present

Specimen 6 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain Present Regionally restricted Expression was detected mostly in the intermediate zone where postmitotic neurons migrate.
TS19: cardiac muscle tissue Present
TS19: dorsal root ganglion Present
TS19: endocardial lining Present
TS19: lens vesicle Present
TS19: retina Present

Specimen 6 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain Present Regionally restricted Expression was detected mostly in the intermediate zone where postmitotic neurons migrate.
TS21: cardiac muscle tissue Present
TS21: dorsal root ganglion Present
TS21: endocardial tissue Present
TS21: lens Present
TS21: liver Present
TS21: metanephros Present
TS21: retina Present
TS21: cochlea Present Regionally restricted Expression was in posterior cochlea.
TS21: adrenal gland Present Regionally restricted Expression was in the medulla.

Specimen 6 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present Regionally restricted Expression was detected mostly in the intermediate zone where postmitotic neurons migrate.
TS23: adrenal medulla Present
TS23: cardiac muscle tissue Present
TS23: dorsal root ganglion Present
TS23: endocardial tissue Present
TS23: lens Present
TS23: liver Present
TS23: lung Present
TS23: metanephros Present
TS23: retina Present
TS23: thymus primordium Present
TS23: cochlea Present Regionally restricted Expression was in posterior cochlea.

Specimen 6 E15.5 male: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: testis Weak

Specimen 6 E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Present Regionally restricted Expression was detected mostly in the intermediate zone where postmitotic neurons migrate.
TS25: lens Weak
TS25: liver Weak
TS25: cochlea Present Regionally restricted Expression was in posterior cochlea.
TS25: adrenal medulla Present
TS25: cardiac muscle tissue Present
TS25: endocardial tissue Present
TS25: lung Present
TS25: metanephros Present
TS25: skin Present
TS25: spleen Present
TS25: thymus Present

Specimen 6 E17.5 male: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: testis Present

Specimen 6 E17.5 female: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: ovary Present

Specimen 6 Birth: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted Expression was in posterior cochlea.
TS27: adrenal medulla Present
TS27: metanephros Present
TS27: spleen Present
TS27: thymus Present

Specimen 6 Birth male: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: testis Present

Specimen 6 Birth female: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: ovary Present

Specimen 6 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted Expression was in posterior cochlea.
TS28: adrenal medulla Present
TS28: metanephros Present
TS28: spleen Present
TS28: thymus Present

Specimen 6 Adult male: postnatal adult (more )
Structure Level Pattern Image Note
TS28: testis Present

Specimen 6 Adult female: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ovary Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory