About   Help   FAQ
Cmc4 Gene Detail
Summary
  • Symbol
    Cmc4
  • Name
    C-X9-C motif containing 4
  • Synonyms
    Mtcp1nb
Location &
Maps
more
  • Sequence Map
    ChrX:74448452-74460190 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    263 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5637812
 protein coding gene ChrX:74448452-74460190 (-)
129S1/SvImJ ENSMUSG00200040923
 protein coding gene ChrX:56464752-56476494 (-)
A/J ENSMUSG00195031158
 protein coding gene ChrX:60189354-60201089 (-)
AKR/J ENSMUSG00220045419
 protein coding gene ChrX:55343685-55355427 (-)
BALB/cJ ENSMUSG00180049238
 protein coding gene ChrX:56764059-56775793 (-)
C3H/HeJ ENSMUSG00175034246
 protein coding gene ChrX:60354556-60366296 (-)
C57BL/6NJ ENSMUSG00215038030
 protein coding gene ChrX:56850042-56861782 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033196
 protein coding gene ChrX:70980672-70992220 (-)
CAST/EiJ ENSTCUG00005038610
 protein coding gene ChrX:58233030-58244767 (-)
CBA/J ENSMUSG00210042840
 protein coding gene ChrX:57034355-57046090 (-)
DBA/2J ENSMUSG00185031915
 protein coding gene ChrX:69456097-69467834 (-)
FVB/NJ ENSMUSG00205035928
 protein coding gene ChrX:56321805-56333542 (-)
JF1/MsJ ENSUMUG00000042135
 protein coding gene ChrX:90291534-90303304 (-)
LP/J ENSMUSG00230035430
 protein coding gene ChrX:76023326-76035068 (-)
NOD/ShiLtJ ENSMUSG00190038568
 protein coding gene ChrX:56274167-56285902 (-)
NZO/HlLtJ ENSMUSG00225047561
 protein coding gene ChrX:81239418-81251157 (-)
PWK/PhJ ENSLUMG00010042517
 protein coding gene ChrX:55912690-55924426 (-)
SPRET/EiJ ENSMSPG00010028299
 protein coding gene ChrX:59304236-59316094 (-)
WSB/EiJ ENSIUOG00005045022
 protein coding gene ChrX:57032817-57044528 (-)



Homology
more
  • Human Ortholog
    CMC4, C-X9-C motif containing 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CMC4, C-X9-C motif containing 4
  • Synonyms
    C6.1B, MTCP1, MTCP1B, MTCP1NB, p8, p8MTCP1
  • Links
    NCBI Gene ID: 100272147
    UniProt: P56277

  • Chr Location
    Xq28; chrX:155061622-155071136 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 105886298 NCBI Gene Model | MGI Sequence Detail 11739 C57BL/6J ±  kb
transcript NM_010839 RefSeq | MGI Sequence Detail 1011 ZRU/MplStud  
polypeptide Q61908 UniProt | EBI | MGI Sequence Detail 68 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5
References
more
  • Summaries
    All 20
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:21838 Soulier J, et al., The MTCP-1/c6.1B gene encodes for a cytoplasmic 8 kD protein overexpressed in T cell leukemia bearing a t(X;14) translocation. Oncogene. 1994 Dec;9(12):3565-70
  • Latest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory