Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Sox10-icre/ERT2)388Wdr
Name:	transgene insertion 388, William D Richardson
MGI ID:	MGI:5634390
Synonyms:	Sox10-iCreERT2, Tg(Sox10-icre/ERT2)#aWdr
Transgene:	Tg(Sox10-icre/ERT2)388Wdr  Location: unknown
Alliance:	Tg(Sox10-icre/ERT2)388Wdr page

Strain of Origin:

C57BL/6 or CBA

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Sox10-icre/ERT2)388Wdr expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Sox10 (MGI:98358)   Mutation details: The transgene was generated using the PAC RP21-427F18. Oligodendrocyte-specific expression of the inducible improved cre recombinase (icre/ERT2) was achieved by replacing the coding sequence of Sox10 with the fusion. Four founders were obtained and one (388) was selected for further study. (J:217432)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox10 (mouse) Summary of all recombinase alleles driven by Sox10. Comparative matrix view of recombinase activities Alliance mouse Sox10 gene page

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(Sox10-icre/ERT2)388Wdr

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:217432 McKenzie IA, et al., Motor skill learning requires active central myelination. Science. 2014 Oct 17;346(6207):318-22
All:	16 reference(s)