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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Sox10-icre/ERT2)388Wdr
transgene insertion 388, William D Richardson
MGI:5634390
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Seh1ltm1Lzha/Seh1ltm1Lzha
Tg(Sox10-icre/ERT2)388Wdr/0 		involves: 129 * C57BL/6 * CBA MGI:6712830


Genotype
MGI:6712830
cn1
Allelic
Composition		 Seh1ltm1Lzha/Seh1ltm1Lzha
Tg(Sox10-icre/ERT2)388Wdr/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Seh1ltm1Lzha mutation (0 available); any Seh1l mutation (84 available)
Tg(Sox10-icre/ERT2)388Wdr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased oligodendrocyte number ( J:276253 )
• mice administered tamoxifen at P3 show a reduction in mature oligodendrocytes at P14
dysmyelination ( J:276253 )
• mice administered tamoxifen at P3 show a reduction in myelination at P14




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory