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Gene Expression Data
Assay Details
Assay
Reference: J:212212 O'Hara L, et al., Targeting of GFP-Cre to the mouse Cyp11a1 locus both drives cre recombinase expression in steroidogenic cells and permits generation of Cyp11a1 knock out mice. PLoS One. 2014;9(1):e84541
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5615899
Gene symbol: Ar
Gene name: androgen receptor
Antibody: anti-androgen receptor (ab74272)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3C control adrenal: postnatal day 100; Artm1Verh/Y (more )
Structure Level Pattern Image Note
TS28: adrenal cortex Present 3C top left
Specimen 3C Cyp11a1-ARKO adrenal: postnatal day 100; Artm1Verh/Y, Cyp11a1tm1(GFP/cre)Pzg/Cyp11a1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: adrenal cortex Absent 3C top right
Specimen 3C control testis: postnatal day 100; Artm1Verh/Y (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 3C bottom left
Specimen 3C Cyp11a1-ARKO testis: postnatal day 100; Artm1Verh/Y, Cyp11a1tm1(GFP/cre)Pzg/Cyp11a1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 3C bottom right In the mutant some Leydig cells retain expression.
Specimen 3D control: postnatal day 100; Artm1Verh/Y (more )
Note: Double labeled: brown - Ar; blue - Hsd3b (assay MGI:5615901
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 3D left
Specimen 3D Cyp11a1-ARKO: postnatal day 100; Artm1Verh/Y, Cyp11a1tm1(GFP/cre)Pzg/Cyp11a1+ (more )
Note: Conditional mutant. Double labeled: brown - Ar; blue - Hsd3b (assay MGI:5615901
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 3D right In the mutant some Leydig cells retain expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory