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Gene Expression Data
Assay Details
Assay
Reference: J:105843 Hakami RM, et al., Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage. Mech Dev. 2006 Feb;123(2):124-34
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5613912
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Reporter: lacZ
Direct Detection
Results
Specimen 1C: embryonic day 10.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present Regionally restricted 1C Expression is in migratory neural crest along the rostral to caudal axis.
Specimen 1D: embryonic day 10.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present 1D Expression is the same as in wild-type.
Specimen 1K: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate 1K Expression is in cells dorsal to the eye.
Specimen 1L: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Weak Punctate 1L Expression is in a small number of cells dorsal to the eye.
Specimen 4E: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Note: The right panel is a higher magnification.
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate 4E left , 4E right Expression is in melanocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory