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Gene Expression Data
Assay Details
Assay
Reference: J:125512 Goto Y, et al., Genetic interactions between activin type IIB receptor and Smad2 genes in asymmetrical patterning of the thoracic organs and the development of pancreas islets. Dev Dyn. 2007 Oct;236(10):2865-74
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5559873
Gene symbol: Ins1
Gene name: insulin I
Antibody: anti-porcine insulin
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3L: embryonic day 18.5 (more )
Note: Double labeled: red - Ins1 and Ins2; green - Gcg (assay MGI:5559874).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 3L Expression is in the core of the round-shaped islets.

Specimen 3P: embryonic day 18.5; Acvr2btm1Enl/Acvr2btm1Enl, Smad2tm1Enl/Smad2+ (more )
Note: Double labeled: red - Ins1 and Ins2; green - Gcg (assay MGI:5559874).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 3P Expression is in the altered-shaped mutant islets.

Specimen 5D upper: embryonic day 18.5 (more )
Note: Double labeled: red - Ins1 and Ins2; green - Gcg (assay MGI:5559874).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 5D upper Expression is in the core of the round-shaped islets.

Specimen 5D lower: embryonic day 18.5; Acvr2btm1Enl/Acvr2btm1Enl, Smad2tm1Enl/Smad2+ (more )
Note: Double labeled: red - Ins1 and Ins2; green - Gcg (assay MGI:5559874).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 5D lower Expression is in the altered-shaped mutant islets.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory