Gene Expression Data
Assay Details
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Assay
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Reference:
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J:143210
Zhou CJ, et al., Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Dev Dyn. 2008 Dec;237(12):3681-9
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5554675
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Gene symbol:
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Aldh1a3
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Gene name:
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aldehyde dehydrogenase family 1, subfamily A3
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Probe:
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Raldh3 probe3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5E:
embryonic day 10.5
(more  )
Specimen
5E:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
5E
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Expression is in the dorsal eyecup and ventral retina.
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Specimen
5F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Lrp6Gt(Ex187)Byg/Lrp6Gt(Ex187)Byg
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
5F
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The expression in the ventral retina has shifted in this mutant.
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Specimen
5G:
embryonic day 10.5
(more )
Specimen
5G:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
5G
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Expression is in the dorsal eyecup and ventral retina.
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| TS17: head |
Present |
Regionally restricted |
5G
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Expression is in the orofacial region.
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Specimen
5H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Lrp6Gt(Ex187)Byg/Lrp6Gt(Ex187)Byg
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Weak |
Regionally restricted |
5H
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Expression is in the dorsal retinal pigmented epithelium.
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| TS17: head |
Strong |
Regionally restricted |
5H
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Expression is in the orofacial region.
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Analysis Tools
