Lrp6Gt(Ex187)Byg
Gene trapped Allele Detail
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Symbol: |
Lrp6Gt(Ex187)Byg |
Name: |
low density lipoprotein receptor-related protein 6; gene trap Ex187, BayGenomics |
MGI ID: |
MGI:2156191 |
Synonyms: |
lrp6-, Lrp6betageo, Lrp6Gt(pGT1.8TM)187Wcs, Lrp6lacZ |
Gene: |
Lrp6 Location: Chr6:134423439-134543876 bp, - strand Genetic Position: Chr6, 65.37 cM
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Alliance: |
Lrp6Gt(Ex187)Byg page
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Lrp6Cd/Lrp6Gt(Ex187)Byg mice reveal a range of phenotypes
Show the 1 phenotype image(s) involving this allele.
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Mutant Cell Line: |
Ex187 |
Germline Transmission: |
Earliest citation of germline transmission:
J:64989
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Parent Cell Line: |
CGR8 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector: pGT1.8TM
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Mutation details: Insertion of a gene trap vector into the gene that joined the first 321 amino acids of the encoded protein in frame to a beta-galactosidase-neomycin resistance reporter gene. Northern blot analysis demonstrated that no normal transcript was encoded by this allele.
(J:64989)
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Inheritance: |
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Recessive |
Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
17 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:37528 Skarnes WC, et al., Capturing genes encoding membrane and secreted proteins important for mouse development. Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6592-6 |
All: |
44 reference(s) |
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