About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:100239 Hinshelwood MM, et al., Temporal and spatial expression of liver receptor homologue-1 (LRH-1) during embryogenesis suggests a potential role in gonadal development. Dev Dyn. 2005 Sep;234(1):159-68
Assay type: RNA in situ
MGI Accession ID: MGI:5544585
Gene symbol: Nr5a1
Gene name: nuclear receptor subfamily 5, group A, member 1
Probe: pSF-13'
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: urogenital ridge Present Expression was throughout the urogenital ridge.

Specimen 1A,1B E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: urogenital ridge Present 1A SF-1 E10.5 , 1B SF-1 E10.5 Expression was detected in somatic cells throughout the urogenital ridge.
TS17: endocrine gland Trace Regionally restricted 1A SF-1 E10.5 Extremely low levels of expression were detected in the adrenal.

Specimen 1A,1B E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 1A SF-1 E11.5 , 1B SF-1 E11.5
TS19: urogenital ridge Present 1B SF-1 E11.5 , 1A SF-1 E11.5 Expression was throughout the urogenital ridge in somatic and germ cells.

Specimen 1A,1B E13.5 Ovary: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: ovary Strong Widespread 1B SF-1 Ovary E13.5 , 1A SF-1 Ovary E13.5 Expression was detected throughout the ovary. Expression was detected in somatic cells and in epithelium surrounding the ovary.

Specimen 1A,1B E13.5 Testis: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: primary sex cord Present Regionally restricted 1B SF-1 Testis E13.5 , 1A SF-1 Testis E13.5 Expression was detected in pre-Sertoli cells.
TS21: interstitium of the testis Strong 1B SF-1 Testis E13.5 , 1A SF-1 Testis E13.5
TS21: adrenal gland Present 1A SF-1 Testis E13.5

Specimen 1A E15.5 Ovary: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: ovary Weak 1A SF-1 Ovary E15.5

Specimen 1A E15.5 Testis: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: interstitium of the testis Present 1A SF-1 Testis E15.5

Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: adrenal gland Present

Specimen 2 P2: postnatal day 2 (more )
Structure Cell Type Level Pattern Image Note
TS27: interstitium of the testis Present 2_SF-1 P2 brightfield , 2_SF-1 P2
TS27: Sertoli cell Sertoli cell Present 2_SF-1 P2 brightfield , 2_SF-1 P2

Specimen 2 P8: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 2_SF-1 P8
TS28: interstitium of the testis Present 2_SF-1 P8 Expression was most abundant in the interstitium.

Specimen 2 P24: postnatal day 24 (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 2_SF-1 P24
TS28: Sertoli cell Sertoli cell Weak 2_SF-1 P24
TS28: epithelium of epididymis Absent 2_SF-1 P24

Specimen 2 Ad: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 2_SF-1 Ad
TS28: Sertoli cell Sertoli cell Weak 2_SF-1 Ad

Specimen 3B: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: interstitium of the testis Present 3B
TS27: Sertoli cell Sertoli cell Present 3B

Specimen 3D cortical region: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: follicle cell of primary follicle Present Regionally restricted 3D left Expression was detected in granulosa cells.
TS27: follicle cell of primordial follicle Present Regionally restricted 3D left Expression was detected in granulosa cells.
TS27: mesenchymal stroma of ovary Present 3D left

Specimen 3D medullary region: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: follicle cell of primary follicle Present Regionally restricted 3D right Expression was detected in granulosa cells.
TS27: follicle cell of primordial follicle Present Regionally restricted 3D right Expression was detected in granulosa cells.
TS27: mesenchymal stroma of ovary Present 3D right

Specimen 4 P2: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: ovary Present Uniform 4_SF-1 P2 Expression was evenly distributed throughout the ovary.

Specimen 4 P8: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: ovary Present Regionally restricted 4_SF-1 P8 Expression was high throughout the medullary portion of the ovary. The cortical region lacked signal.
TS28: ovary follicle Present Regionally restricted 4_SF-1 P8 Expression was detected in granulosa cells.
TS28: ovary theca Present 4_SF-1 P8

Specimen 4 P24: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: ovary Present Regionally restricted 4_SF-1 P24 Expression was detected in both the cortex and medulla. Strongest signal was in the theca interna and interstitium.
TS28: ovary theca Strong 4_SF-1 P24

Specimen 4 Ad: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ovary Present Regionally restricted 4_SF-1 Ad Expression was detected in both the cortex and medulla. Strongest signal was in the theca interna and interstitium.
TS28: ovary theca Strong 4_SF-1 Ad


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory