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Gene Expression Data
Assay Details
Assay
Reference: J:119933 Lewis SL, et al., Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse. Mech Dev. 2007 Feb;124(2):157-165
Assay type: RNA in situ
MGI Accession ID: MGI:5532299
Gene symbol: Gsc
Gene name: goosecoid homeobox
Probe: Gsc probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1N: embryonic day 7.0 (more )
Note: Mid-streak embryo.
Structure Level Pattern Image Note
TS10: embryo endoderm Present Regionally restricted 1N Expression was detected in the anterior endoderm.
TS10: primitive streak Present Regionally restricted 1N Expression was detected in the anterior primitive streak.

Specimen 1O: embryonic day 7.0 (more )
Note: Mid-streak embryo.
Structure Level Pattern Image Note
TS10: embryo endoderm Present Regionally restricted 1O Expression was detected in the anterior endoderm.
TS10: primitive streak Present Regionally restricted 1O Expression was detected in the anterior primitive streak.

Specimen 1P: embryonic day 7.0 (more )
Note: Mid-streak embryo. Double labeled: orange/brown - Gsc; purple - Dkk1 (assay MGI:5532291).
Structure Level Pattern Image Note
TS10: embryo endoderm Present Regionally restricted 1P Expression was detected in the anterior endoderm. There was overlap with Dkk1 expression in the prechordal region.
TS10: primitive streak Present Regionally restricted 1P Expression was detected in the anterior primitive streak.

Specimen 1Q: embryonic day 7.0 (more )
Note: Late-streak embryo.
Structure Level Pattern Image Note
TS10: embryo endoderm Present Regionally restricted 1Q Expression was detected in the anterior and distal endoderm.

Specimen 1S: embryonic day 8.0 (more )
Note: Early head-fold embryo.
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 1S Expression was detected in the prechordal tissue.

Specimen 2A: embryonic day 7.0; Dkk1tm1Lmgd/Dkk1tm1Lmgd (more )
Note: Mid-streak embryo.
Structure Level Pattern Image Note
TS10: embryo endoderm Present Regionally restricted 2A Expression was detected in the anterior endoderm as in wild type.
TS10: primitive streak Present Regionally restricted 2A Expression was detected in the anterior primitive streak as in wild type.

Specimen 2C: embryonic day 8.0 (more )
Note: Early head-fold embryo.
Structure Level Pattern Image Note
TS12: mesenchyme derived from head mesoderm Present Regionally restricted 2C Expression was detected in the prechordal mesoderm.

Specimen 2D: embryonic day 8.0; Dkk1tm1Lmgd/Dkk1tm1Lmgd (more )
Note: Early head-fold embryo.
Structure Level Pattern Image Note
TS12: mesenchyme derived from head mesoderm Present Regionally restricted 2D Expression was present, but reduced in the prechordal mesoderm of the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory