Gene Expression Image Detail

Reference

Figure

ID

J:119933 Lewis SL, et al., Mech Dev. 2007 Feb;124(2):157-165

1

MGI:5529640

Image

Caption

(A-D,G,J,L-S) Whole mount in situ hybridization. (E,F,H,I,K) Sections from wholemount in situ hybridization. (A) pre-streak (E6.0) embryo; (B) mid-streak (E7.0) embryo; (C) late-streak (E7.5) embryo (en-face view); (D) early-head-fold stage (E7.75) embryo (dotted lines indicate plane of section shown in E and F). (G-K) E8.5 embryo. (G) dorsal view; (J) dotted line indicates plane of section shown in K; (L) mid-streak embryo, anterior endoderm (asterisk), lateral view; (M) mid-streak embryo, en face view. (N) mid-streak embryo, lateral view; (O) mid-streak embryo, en face view (note that this embryo is dissected in half in the en face view to remove the posterior staining). (P) Dual in situ hybridization - Dkk1 (purple staining and arrow pointing to expression in the anterior endoderm) and Gsc (orange brown staining; arrow pointing to expression in the anterior primitive streak and dashed line marking the domain in the anterior endoderm) of the mid-streak embryo. (Q) distal endoderm (arrow), late-streak stage embryo. (R and S) early-head-fold stage embryos.

Copyright

Reprinted with permission from Elsevier from 10.1016/j.mod.2006.10.001 Mech Dev 124: 157-165, Lewis SL; Khoo PL; Andrea De Young R; Bildsoe H; Wakamiya M; Behringer RR; Mukhopadhyay M; Westphal H; Tam PP, Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse. Copyright 2007

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:5532291 (Dkk1)
B	MGI:5532291 (Dkk1)
C	MGI:5532291 (Dkk1)
D	MGI:5532291 (Dkk1)
E	MGI:5532291 (Dkk1)
F	MGI:5532291 (Dkk1)
G	MGI:5532291 (Dkk1)
H	MGI:5532291 (Dkk1)
I	MGI:5532291 (Dkk1)
J	MGI:5532291 (Dkk1)
K	MGI:5532291 (Dkk1)
L	MGI:5532291 (Dkk1)
M	MGI:5532291 (Dkk1)
N	MGI:5532299 (Gsc)
O	MGI:5532299 (Gsc)
P	MGI:5532291 (Dkk1) MGI:5532299 (Gsc)
Q	MGI:5532299 (Gsc)
R	MGI:5532291 (Dkk1)
S	MGI:5532299 (Gsc)