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Gene Expression Data
Assay Details
Assay
Reference: J:58233 Eisenstat DD, et al., DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation. J Comp Neurol. 1999 Nov 15;414(2):217-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5523056
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Antibody: C199
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2D: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon Present 2D Expression is in the subcortical telencephalon, itincludes the large ganglionic eminence, the medial ganglionic eminence, the preoptic area, the anterior entopeduncular area, and parts of the septal and amygdalar primordia.
TS18: diencephalon Present Regionally restricted 2D Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.
TS18: diencephalon lateral wall ventricular layer Strong Regionally restricted 2D
TS18: telencephalon ventricular layer Strong Regionally restricted 2D
TS18: diencephalon lateral wall mantle layer Weak Regionally restricted 2D
TS18: telencephalon mantle layer Weak Regionally restricted 2D
Specimen 2J: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon ventricular layer Strong 2J
TS18: telencephalon mantle layer Weak 2J
Specimen 2P: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon ventricular layer Strong 2P
TS18: telencephalon mantle layer Weak 2P
Specimen 3G: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3G Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.
Specimen 3J: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3J Expression is in the supraoptoparaventricular area and ventral thalamus with a caudal limit at the zona limitans intrathalamica.
Specimen 3R: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3R Expression is in the hypothalamus.
Specimen 4D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Present 4D
Specimen 4J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: caudal ganglionic eminence Present Regionally restricted 4J Expression is in the subpallial part.
TS20: telencephalon Present Regionally restricted 4J Expression is in the preoptic area.
TS20: diencephalon Present Regionally restricted 4J Expression is in periventricular cell populations that may contribute to the zona incerta and to the paraventricular nucleus.
Specimen 4M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus Present Regionally restricted 4M
Specimen 4P: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus Present Regionally restricted 4P
Specimen 5B: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2 protein; blue/purple - Dlx2 RNA (assay MGI:5523240).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5B Expression is in the medial ganglionic eminence (shown is the ventricular zone).
Specimen 5C: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2 protein; blue/purple - Dlx2 RNA (assay MGI:5523240).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5C Expression is in the medial ganglionic eminence (shown is the subventricular zone).
Specimen 5H: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2; blue/purple - Dlx1 (assay MGI:5523863).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5H Expression is in the medial ganglionic eminence.
Specimen 5I: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2; blue/purple - Dlx1 (assay MGI:5523863).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5I Expression is in the medial ganglionic eminence (shown is the ventricular zone).
Specimen 5J: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2; blue/purple - Dlx1 (assay MGI:5523863).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5J Expression is in the medial ganglionic eminence (shown is the subventricular zone).
Specimen 5O: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2; blue/purple - Dlx5 (assay MGI:5523864).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5O Expression is in the medial ganglionic eminence.
Specimen 5P: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2; blue/purple - Dlx5 (assay MGI:5523864).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5P Expression is in the medial ganglionic eminence (shown is the ventricular zone).
Specimen 5Q: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx2; blue/purple - Dlx5 (assay MGI:5523864).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5Q Expression is in the medial ganglionic eminence (shown is the subventricular zone).
Specimen 9F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9F Expression is in the ganglionic eminence in the ventricular zone and subpallially .
Specimen 10A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present 10A
TS20: cornea Absent 10A
TS20: lens vesicle Absent 10A
TS20: pigmented retinal epithelium Absent 10A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory