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Gene Expression Data
Assay Details
Assay
Reference: J:57262 Song J, et al., The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice. Dev Biol. 1999 Sep 1;213(1):157-69
Assay type: RNA in situ
MGI Accession ID: MGI:5491487
Gene symbol: Hesx1
Gene name: homeobox gene expressed in ES cells
Probe: Hesx1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Expression was detected using NBT/BCIP for the color reaction.
Results
Specimen 4A: embryonic day 7.5 (more )
Note: Double labeled: purple - Hesx1; orange - T (assay MGI:5491484).
Structure Level Pattern Image Note
TS11: anterior visceral endoderm Present 4A
Specimen 4B: embryonic day 8.5 (more )
Note: Double labeled: purple - Hesx1; orange - T (assay MGI:5491484).
Structure Level Pattern Image Note
TS13: neural ectoderm Present Regionally restricted 4B Expression in anterior neural ectoderm.
Specimen 4C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Present Regionally restricted 4C Expression in anterior neural ectoderm.
Specimen 4F: embryonic day 7.5; Acvr2atm1Hsch/Acvr2atm1Hsch, Acvr2btm1Enl/Acvr2b+ (more )
Note: Double labeled: purple - Hesx1; orange - T (assay MGI:5491484).
Structure Level Pattern Image Note
TS11: primitive endoderm Present Regionally restricted 4F Expression is detected in the distal region.
Specimen 4G: embryonic day 8.5; Acvr2atm1Hsch/Acvr2atm1Hsch, Acvr2btm1Enl/Acvr2b+ (more )
Note: Double labeled: purple - Hesx1; orange - T (assay MGI:5491484).
Structure Level Pattern Image Note
TS13: neural ectoderm Weak Regionally restricted 4G Expression is significantly reduced, with a discernible anterior-posterior axis.
Specimen 4H: embryonic day 8.5; Acvr2atm1Hsch/Acvr2atm1Hsch, Acvr2btm1Enl/Acvr2b+ (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Absent 4H No expression is detected in embryos with more severe gastrulation defects.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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