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Esp4 Gene Detail
Summary
  • Symbol
    Esp4
  • Name
    exocrine gland secreted peptide 4
  • Synonyms
    Gm20580
  • Feature Type
    protein coding gene
  • IDs
    MGI:5295687
    NCBI Gene: 100126777
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr17:40909485-40913509 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5295687
 protein coding gene Chr17:40909485-40913509 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023757
 protein coding gene Chr17:41414605-41418628 (+)
A/J MGP_AJ_G0023715
 protein coding gene Chr17:40479550-40483574 (+)
AKR/J MGP_AKRJ_G0023687
 protein coding gene Chr17:40618163-40622186 (+)
BALB/cJ MGP_BALBcJ_G0023719
 protein coding gene Chr17:40345143-40349167 (+)
C3H/HeJ MGP_C3HHeJ_G0023484
 protein coding gene Chr17:41307287-41311310 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024161
 protein coding gene Chr17:43257017-43261041 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022965
 protein coding gene Chr17:41326188-41330211 (+)
CBA/J MGP_CBAJ_G0023460
 protein coding gene Chr17:44740838-44744861 (+)
DBA/2J MGP_DBA2J_G0023585
 protein coding gene Chr17:39275712-39279736 (+)
FVB/NJ MGP_FVBNJ_G0023552
 protein coding gene Chr17:38888998-38893022 (+)
LP/J MGP_LPJ_G0023666
 protein coding gene Chr17:42024376-42028399 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023581
 protein coding gene Chr17:44203337-44207361 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024207
 protein coding gene Chr17:40944557-40948581 (+)
PWK/PhJ MGP_PWKPhJ_G0022709
 protein coding gene Chr17:38630529-38634553 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0023030
 protein coding gene Chr17:41500530-41504554 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100126777 NCBI Gene Model | MGI Sequence Detail 4025 C57BL/6J ±  kb
transcript NM_001177583 RefSeq | MGI Sequence Detail 553 ZRU/MplStud  
polypeptide NP_001171054 RefSeq | MGI Sequence Detail 117 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR043126 Esp1, core domain
    IPR032253 Exocrine gland-secreted peptide Esp1/Esp22
References
more
  • Summaries
    All 9
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:174752 Kimoto H, et al., Sex- and strain-specific expression and vomeronasal activity of mouse ESP family peptides. Curr Biol. 2007 Nov 6;17(21):1879-84
  • Latest
    J:195034 Karn RC, et al., The roles of gene duplication, gene conversion and positive selection in rodent Esp and Mup pheromone gene families with comparison to the Abp family. PLoS One. 2012;7(10):e47697
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory