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Mroh6 Gene Detail
Summary
  • Symbol
    Mroh6
  • Name
    maestro heat-like repeat family member 6
  • Synonyms
    Gm19570
  • Feature Type
    protein coding gene
  • IDs
    MGI:5011755
    NCBI Gene: 223645
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75755986-75760619 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5011755
protein coding gene Chr15:75753085-75762544 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021961
protein coding gene Chr15:75931678-75936311 (-)
A/J MGP_AJ_G0021919
protein coding gene Chr15:73166041-73170673 (-)
AKR/J MGP_AKRJ_G0021902
protein coding gene Chr15:75144808-75149441 (-)
BALB/cJ MGP_BALBcJ_G0021928
protein coding gene Chr15:73182359-73191468 (-)
C3H/HeJ MGP_C3HHeJ_G0021700
protein coding gene Chr15:75205891-75210523 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022368
protein coding gene Chr15:78770166-78774860 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019899
protein coding gene Chr15:69838431-69843009 (-)
CAST/EiJ MGP_CASTEiJ_G0021219
protein coding gene Chr15:75988832-75993459 (-)
CBA/J MGP_CBAJ_G0021667
protein coding gene Chr15:81284700-81289333 (-)
DBA/2J MGP_DBA2J_G0021792
protein coding gene Chr15:72696816-72701446 (-)
FVB/NJ MGP_FVBNJ_G0021773
protein coding gene Chr15:71746429-71751678 (-)
LP/J MGP_LPJ_G0021863
protein coding gene Chr15:76013430-76018062 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021797
protein coding gene Chr15:86588020-86592651 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022388
protein coding gene Chr15:75389505-75394136 (-)
PWK/PhJ MGP_PWKPhJ_G0020960
protein coding gene Chr15:72832640-72837267 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020799
protein coding gene Chr15:75119447-75124048 (-)
WSB/EiJ MGP_WSBEiJ_G0021271
protein coding gene Chr15:75475748-75480378 (-)



Homology
more
  • Human Ortholog
    MROH6, maestro heat like repeat family member 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH6, maestro heat like repeat family member 6
  • Synonyms
    C8orf73
  • Links
    NCBI Gene ID: 642475
    neXtProt AC: NX_A6NGR9
    UniProt: A6NGR9

  • Chr Location
    8q24.3; chr8:143566192-143572772 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    2
  • Gene trapped
    3
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Mroh6
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000098678 Ensembl Gene Model | MGI Sequence Detail 4634 C57BL/6J ±  kb
transcript ENSMUST00000184858 Ensembl | MGI Sequence Detail 2216 Not Applicable  
polypeptide ENSMUSP00000139029 Ensembl | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR045206 Maestro heat-like repeat-containing protein
    IPR048465 Maestro, HEAT repeats
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 35
    Diseases 1
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory