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Gene Expression Data
Assay Details
Assay
Reference: J:106092 Tissir F, et al., Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci. 2006 Feb;23(3):597-607
Assay type: RNA in situ
MGI Accession ID: MGI:4946662
Gene symbol: Fzd3
Gene name: frizzled class receptor 3
Probe: Fzd3 cDNA3
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain Present 1B Expression was equally strong in ventricular zones and in postmitotic differentiation fields.
TS17: brain ventricular layer Present 1B Expression was equally strong in ventricular zones and in postmitotic differentiation fields.
TS17: peripheral nervous system Present Regionally restricted 1B Expression detected in peripheral ganglia.
TS17: limb Weak 1B
TS17: nasal epithelium Weak 1B
TS17: tail Weak 1B

Specimen 2D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nervous system Present 2D
TS20: lens vesicle Moderate 2D
TS20: skin Moderate 2D

Specimen 2E & 2F: embryonic day 12.5 (more )
Note: Fig. 2F is a higher magnification image of the boxed region if Fig. 2E.
Structure Level Pattern Image Note
TS20: brain Present 2F , 2E Expression was equally distributed in ventricular zone and postmitotic differentiation fields.
TS20: brain ventricular layer Present 2F , 2E Expression was equally distributed in ventricular zone and postmitotic differentiation fields.

Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Present 3B
TS22: nervous system Present Non-Uniform 3B Expression in the nervous system was higher in ventricular zones than in migratory and postmitotic differentiation fields.

Specimen Table 2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brainstem Present Regionally restricted Expression was present in the reticular formation and the cochleovestibular nuclei.
TS25: cerebellum Strong Regionally restricted Expression was high in the external granule layer.
TS25: diencephalon ventricular layer Strong
TS25: midbrain ventricular layer Strong
TS25: hypothalamus Present
TS25: midbrain tegmentum Present
TS25: tectum Present
TS25: thalamus Present Regionally restricted Expression was present in the dorsal and ventral thalamus.
TS25: retina Strong Regionally restricted Expression was high in the ventricular zone and ganglion cells.
TS25: cortical plate Present Regionally restricted Expression was high in the ventricular zone/subventricular zone and present in the cortical plate proper.
TS25: corpus striatum Present Regionally restricted Expression was high in the striatum ventricular zone/subventricular zone and present in the striatum.
TS25: main olfactory bulb Present Regionally restricted Expression was high in the olfactory bulb and present in the mitral cells.

Specimen 4B1: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Present 4B1
TS25: cerebellum Present Regionally restricted 4B1 Expression was detected in the external granule layer.

Specimen 4B2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Present 4B2
TS25: pituitary gland Strong 4B2

Specimen 4B3: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Present 4B3

Specimen 4B4: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: hair follicle Present 4B4
TS25: olfactory epithelium Present 4B4
TS25: retina Present 4B4
TS25: skin Present 4B4
TS25: tooth epithelium Present 4B4

Specimen 5C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain Present Widespread 5C Expression was expressed all over the brain. The signal was higher in periventricular areas than in neuronal differentiating fields.

Specimen 5D: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain Present Widespread 5D Expression was expressed all over the brain. The signal was higher in periventricular areas than in neuronal differentiating fields.
TS27: rostral migratory stream Very strong 5D Expression was very strong in the rostral migratory stream.

Specimen Table 3: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present
TS28: dentate gyrus Present
TS28: hippocampus pyramidal cell layer Present
TS28: main olfactory bulb granule cell layer Present
TS28: main olfactory bulb mitral cell layer Present
TS28: diencephalon Ambiguous Regionally restricted Expression was very low or undetectable in the diencephalon ventricular zone.
TS28: dorsal thalamus Ambiguous Expression was very low or undetectable.
TS28: hypothalamus Ambiguous Expression was very low or undetectable.
TS28: prethalamus Ambiguous Expression was very low or undetectable.
TS28: cerebral cortex Present Regionally restricted Expression was detected in the cortical plate ventricular zone/subventricular zone and the cortical plate proper.
TS28: corpus striatum Present Regionally restricted Expression was present in the striatum and the ventricular zone/subventricular zone.
TS28: rostral migratory stream Present

Specimen 6D: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong 6D
TS28: neocortex Strong Regionally restricted 6D Expression was strong in the superficial tier of the neocortical cortical plate.

Specimen 6E: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: rostral migratory stream Strong 6E Expression was strong in the rostral migratory stream.
TS28: dentate gyrus Strong 6E
TS28: hippocampus Strong 6E

Specimen 6F: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Strong 6F

Specimen 7B: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: rostral migratory stream Moderate 7B Expression was moderate in the rostral migratory stream.
TS28: cerebellum internal granule cell layer Moderate 7B
TS28: dentate gyrus Moderate 7B
TS28: corpus striatum Weak 7B
TS28: hippocampus pyramidal cell layer Weak 7B
TS28: neocortex Weak Regionally restricted 7B Expression was weak in the outer tiers of the cortical plate.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory