About   Help   FAQ
Igkv5-43 Gene Detail
Summary
  • Symbol
    Igkv5-43
  • Name
    immunoglobulin kappa chain variable 5-43
  • Feature Type
    gene segment
  • IDs
    MGI:4943320
    NCBI Gene: 381783
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:69800339-69800895 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 31.63 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    17 from dbSNP Build 142
  • Strain Annotations
    11
  • RFLP
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4943320
 gene segment Chr6:69800339-69800927 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000156
 gene segment Chr6:70120935-70121523 (-)
A/J MGP_AJ_G0000138
 gene segment Chr6:67283543-67284131 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0000132
 gene segment Chr6:67488504-67489092 (-)
C3H/HeJ MGP_C3HHeJ_G0000118
 gene segment Chr6:114889266-114889815 (+)
C57BL/6NJ MGP_C57BL6NJ_G0000195
 gene segment Chr6:71925439-71926027 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0000137
 gene segment Chr6:74693177-74693765 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0000128
 gene segment Chr6:66178217-66178805 (-)
LP/J MGP_LPJ_G0000158
 gene segment Chr6:69929229-69929817 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0000141
 gene segment Chr6:78396401-78396989 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000176
 gene segment Chr6:69276041-69276629 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGKV6-21, immunoglobulin kappa variable 6-21 (non-functional)
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV6-21, immunoglobulin kappa variable 6-21 (non-functional)
  • Synonyms
    A26, IGKV621
  • Links
    NCBI Gene ID: 28906
    UniProt: A0A0C4DH24

  • Chr Location
    2p11.2; chr2:89159751-89160366 (-)  GRCh38
  • Human Ortholog
    IGKV6D-21, immunoglobulin kappa variable 6D-21 (non-functional)
  • Synonyms
    A10, IGKV6D21
  • Links
    NCBI Gene ID: 28870
    UniProt: A0A0A0MT36

  • Chr Location
    2p11.2; chr2:90021567-90022185 (+)  GRCh38
  • Human Ortholog
    IGKV6D-41, immunoglobulin kappa variable 6D-41 (non-functional)
  • Synonyms
    A14
  • Links
    NCBI Gene ID: 28869
    UniProt: A0A0C4DH26

  • Chr Location
    2p11.2; chr2:90069662-90070240 (+)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 381783 NCBI Gene Model | MGI Sequence Detail 557 C57BL/6J ±  kb
transcript M16162 GenBank | ENA | DDBJ | MGI Sequence Detail 420 Not Specified  
polypeptide A0A0B4J1J2 UniProt | EBI | MGI Sequence Detail 115 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 14
    cDNA 3
    Primer pair 1
    Other 2
Other
Accession IDs
less
MGD-MRK-11312, MGI:96509
References
more
  • Summaries
    All 18
    Gene Ontology 1
  • Earliest
    J:27711 Nishioka Y, et al., Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes. J Biol Chem. 1980 Apr 25;255(8):3691-4
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory