Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tmed299J
Name:	transmembrane p24 trafficking protein 2; line 99J
MGI ID:	MGI:4456438
Gene:	Tmed2  Location: Chr5:124678835-124688566 bp, + strand  Genetic Position: Chr5, 63.65 cM
Alliance:	Tmed299J page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Nucleotide substitutions   Mutation details: ENU mutagenesis induced a C to A transversion in exon 1 that results in the amino acid substitution of glutamic acid for alanine at position 12 (A13E). The absence of protein expression was confirmed by western blot analysis on E9.5 extracts. (J:160012)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	62 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmed2 Mutation:	7 strains or lines available

Original:	J:160012 Jerome-Majewska LA, et al., The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. Dev Biol. 2010 May 1;341(1):154-66
All:	5 reference(s)