Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(RP23-65I14)1Jno
Name:	transgene insertion 1, Jeffrey L Noebels
MGI ID:	MGI:3842797
Synonyms:	alpha1G-Tg1
Transgene:	Tg(RP23-65I14)1Jno  Location: unknown
Alliance:	Tg(RP23-65I14)1Jno page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(RP23-65I14)1Jno expresses 3 genes Transgene expresses: Organism Expressed Gene Note mouse Abcc3 (MGI:1923658) mouse Ankrd40 (MGI:1918702) mouse Cacna1g (MGI:1201678)   Mutation details: This transgene consists of the mouse BAC RP23-65114 (GenBank id AL64596) containing the full coding sequence for Cacna1g, Abcc3, and Ankrd40 along with the 5' end of 330000P08Rik and the 3' end of Spata20. This line has1 to 2 transgene copy integrations. Overexpression of Cacna1g in the brain was verified by quantitative RT-PCR and western blot analysis. (J:146431)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:146431 Ernst WL, et al., Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy. J Neurosci. 2009 Feb 11;29(6):1615-25
All:	1 reference(s)