Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(PGK1-KITLG*220)441Daw
Name:	transgene insertion 441, David A Williams
MGI ID:	MGI:3817558
Synonyms:	SCF220, Tg(huSCFh220)441Daw, TgN(PGKhSCF220)
Transgene:	Tg(PGK1-KITLG*220)441Daw  Location: unknown
Alliance:	Tg(PGK1-KITLG*220)441Daw page

Strain of Origin:

C3H/HeJ

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(PGK1-KITLG*220)441Daw expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human KITLG (4254) Kitl  (MGI:96974)   Mutation details: A 1.3 kb fragment containing a minigene with the human PGK1 promoter, splice donor/splice acceptor (SD/SA) sequence, a human stem cell factor (hSCF or KITLG) cDNA encoding the 220 amino acid isoform, and a polyA sequence was injected into the pronuclei of fertilized C3H/HeJ eggs. (J:32600)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:32600 Majumdar MK, et al., Xenogeneic expression of human stem cell factor in transgenic mice mimics codominant c-kit mutations. Blood. 1996 Apr 15;87(8):3203-11
All:	7 reference(s)