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CrygdL23
Chemically induced Allele Detail
Summary
Symbol: CrygdL23
Name: crystallin, gamma D; L23
MGI ID: MGI:3762620
Synonyms: Crygdm1Btlr, gamma D (V76)
Gene: Crygd  Location: Chr1:65101031-65102611 bp, - strand  Genetic Position: Chr1, 32.8 cM
Alliance: CrygdL23 page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsA T-to-A transversion found within the gene is predicted to result in a substitution of valine at position 76 with an aspartate in the encoded protein. (J:126881)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crygd Mutation:  16 strains or lines available
References
Original:  J:126881 Wang K, et al., GammaD-crystallin associated protein aggregation and lens fiber cell denucleation. Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3719-28
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory