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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
CrygdL23
L23
MGI:3762620
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
CrygdL23/CrygdL23 involves: C57BL/6J MGI:3762624
ht2
CrygdL23/Crygd+ involves: C57BL/6J MGI:3762625


Genotype
MGI:3762624
hm1
Allelic
Composition
CrygdL23/CrygdL23
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygdL23 mutation (1 available); any Crygd mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• incomplete denucleation and removal of other cell organalles is observed 1 day after birth
• develop whole cataracts
• lens of 3 day old mice are resistant to ex vivo cold-induced cataract formation
• slightly small lenses are observed
• posterior face of lens ruptures by one week post birth




Genotype
MGI:3762625
ht2
Allelic
Composition
CrygdL23/Crygd+
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygdL23 mutation (1 available); any Crygd mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• incomplete denucleation of lens fibers is observed as late as day 21 post birth
• develop whole cataracts
• lens of 3 day old mice are resistant to ex vivo cold-induced cataract formation
• slightly small lenses are observed





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory