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Cyp4a30b Gene Detail
Summary
  • Symbol
    Cyp4a30b
  • Name
    cytochrome P450, family 4, subfamily a, polypeptide 30b
  • Synonyms
    Cyp4a30b-ps, OTTMUSG00000008626
  • Feature Type
    protein coding gene
  • IDs
    MGI:3717145
    NCBI Gene: 435802
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:115309801-115328259 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.02 cM
Strain
Comparison
more
  • SNPs within 2kb
    87 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3717145
 protein coding gene Chr4:115309688-115328615 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028600
 protein coding gene Chr4:116252630-116277817 (+)
A/J MGP_AJ_G0028560
 protein coding gene Chr4:111819587-111829139 (+)
AKR/J MGP_AKRJ_G0028510
 protein coding gene Chr4:114144238-114167908 (+)
BALB/cJ MGP_BALBcJ_G0028582
 protein coding gene Chr4:112432555-112452250 (+)
C3H/HeJ MGP_C3HHeJ_G0028296
 protein coding gene Chr4:115744552-115753426 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029023
 protein coding gene Chr4:120744532-120781524 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027730
 protein coding gene Chr4:112980023-113039449 (+)
CBA/J MGP_CBAJ_G0028263
 protein coding gene Chr4:123938224-123954075 (+)
DBA/2J MGP_DBA2J_G0028411
 protein coding gene Chr4:112474664-112497670 (+)
FVB/NJ MGP_FVBNJ_G0028379
 protein coding gene Chr4:110939323-110969554 (+)
LP/J MGP_LPJ_G0028514
 protein coding gene Chr4:116418190-116470700 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028406
 protein coding gene Chr4:129061180-129068570 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029062
 protein coding gene Chr4:115365162-115402118 (+)
PWK/PhJ MGP_PWKPhJ_G0027455
 protein coding gene Chr4:109102891-109128643 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027282
 protein coding gene Chr4:111664336-111702023 (+)
WSB/EiJ MGP_WSBEiJ_G0027811
 protein coding gene Chr4:115203606-115235920 (+)



Homology
more
  • Human Ortholog
    CYP4A11, cytochrome P450 family 4 subfamily A member 11
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP4A11, cytochrome P450 family 4 subfamily A member 11
  • Synonyms
    CP4Y, CYP4A2, CYP4AII, CYPIVA11
  • Links
    NCBI Gene ID: 1579
    neXtProt AC: NX_Q02928
    UniProt: Q02928

  • Chr Location
    1p33; chr1:46929177-46941484 (-)  GRCh38
  • Human Ortholog
    CYP4A22, cytochrome P450 family 4 subfamily A member 22
  • Links
    NCBI Gene ID: 284541
    neXtProt AC: NX_Q5TCH4
    UniProt: Q5TCH4

  • Chr Location
    1p33; chr1:47137435-47149727 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CYP4A11 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Cyp4a30b
  • Find Mice (IMSR)
    19 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000084346 Ensembl Gene Model | MGI Sequence Detail 18459 C57BL/6J ±  kb
transcript ENSMUST00000119958 Ensembl | MGI Sequence Detail 1527 Not Applicable  
polypeptide ENSMUSP00000140857 Ensembl | MGI Sequence Detail 508 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR036396 Cytochrome P450 superfamily
Other
Accession IDs
less
MGI:3650997
References
more
  • Summaries
    All 17
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:148802 Boles MK, et al., A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet. 2009;10:12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory