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Srp54c Gene Detail
Summary
  • Symbol
    Srp54c
  • Name
    signal recognition particle 54C
  • Synonyms
    E330029E12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3714359
    NCBI Gene: 100101806
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr12:55276953-55310621 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 23.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3714359
 protein coding gene Chr12:55276896-55326120 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019744
 protein coding gene Chr12:54049837-54076685 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0019676
 protein coding gene Chr12:53929851-53973485 (+)
BALB/cJ MGP_BALBcJ_G0019683
 protein coding gene Chr12:52430344-52468886 (+)
C3H/HeJ MGP_C3HHeJ_G0019486
 protein coding gene Chr12:53827080-53862286 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020135
 protein coding gene Chr12:55868831-55906007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017754
 protein coding gene Chr12:50404743-50439276 (+)
CAST/EiJ MGP_CASTEiJ_G0019039
 protein coding gene Chr12:48860082-48894903 (+)
CBA/J MGP_CBAJ_G0019458
 protein coding gene Chr12:57815431-57862238 (+)
DBA/2J MGP_DBA2J_G0019572
 protein coding gene Chr12:51988045-52030562 (+)
FVB/NJ MGP_FVBNJ_G0019561
 protein coding gene Chr12:51463929-51494138 (+)
LP/J MGP_LPJ_G0019644
 protein coding gene Chr12:54103147-54145861 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019597
 protein coding gene Chr12:59226922-59371862 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020169
 protein coding gene Chr12:53205382-53239706 (+)
PWK/PhJ MGP_PWKPhJ_G0018806
 protein coding gene Chr12:46564954-46599499 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018600
 protein coding gene Chr12:47787989-47807633 (+)
WSB/EiJ MGP_WSBEiJ_G0019090
 protein coding gene Chr12:53866185-53915948 (+)



Homology
more
  • Human Ortholog
    SRP54, signal recognition particle 54
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SRP54, signal recognition particle 54
  • Synonyms
    SCN8
  • Links
    NCBI Gene ID: 6729
    neXtProt AC: NX_P61011
    UniProt: P61011

  • Chr Location
    14q13.2; chr14:34981957-35029686 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SRP54 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079108 Ensembl Gene Model | MGI Sequence Detail 33669 C57BL/6J ±  kb
transcript ENSMUST00000218879 Ensembl | MGI Sequence Detail 3642 Not Applicable  
polypeptide ENSMUSP00000151681 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
    3.6.5.-
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR028260 FAM177 family
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR013822 Signal recognition particle SRP54, helical bundle
    IPR042101 Signal recognition particle SRP54, N-terminal domain superfamily
    IPR022941 Signal recognition particle, SRP54 subunit
    IPR006325 Signal recognition particle, SRP54 subunit, eukaryotic
    IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain
    IPR004125 Signal recognition particle, SRP54 subunit, M-domain
    IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
Other
Accession IDs
less
MGI:2442031
References
more
  • Summaries
    All 22
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory