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Gene Expression Data
Assay Details
Assay
Reference: J:21078 Ohuchi H, et al., Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis. Biochem Biophys Res Commun. 1994 Oct 28;204(2):882-8
Assay type: RNA in situ
MGI Accession ID: MGI:3712443
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: pBSF8
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen Not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: primitive streak Present Expression is present along the midline of the posterior half of the embryo where cells in the epiblast accumulte to form the primitive streak.
Specimen 1A: embryonic day 8.0 (more )
Note: This is a dorsal view.
Structure Level Pattern Image Note
TS12: primitive streak Present 1A
TS12: future midbrain Present 1A Expression is present in the cephalic neural folds above the pre-otic sulcus in an area corresponding to the prospective midbrain.
Specimen Not shown: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted Expression is present at the future midbrain-hindbrain border.
TS12: future midbrain Present Regionally restricted Expression is present at the future midbrain-hindbrain border.
Specimen 1B: embryonic day 8.75 (more )
Note: This is a lateral view.
Structure Level Pattern Image Note
TS14: future hindbrain Present Regionally restricted 1B Expression is present in the midbrain-hindbrain border.
TS14: future midbrain Present Regionally restricted 1B Expression is present in the midbrain-hindbrain border.
TS14: primitive streak Strong 1B
TS14: prosencephalon Present Regionally restricted 1B Expression is present in the rostral forebrain (the future olfactory bulb).
TS14: 1st branchial arch maxillary component ectoderm Present 1B
Specimen 1C: embryonic day 9.5 (more )
Note: This is a lateral view.
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 1C Expression is present in the midbrain-hindbrain border.
TS15: future midbrain Present Regionally restricted 1C Expression is present in the midbrain-hindbrain border.
TS15: telencephalon Present Regionally restricted 1C Expression is present in the rostral forebrain (the future olfactory bulb).
TS15: 1st branchial arch mandibular component ectoderm Present 1C
TS15: 1st branchial arch maxillary component ectoderm Present 1C
Specimen 1D: embryonic day 9.5 (more )
Note: This is a frontal view.
Structure Level Pattern Image Note
TS15: olfactory placode Present 1D Expression is present in the prospective nasal placode.
TS15: telencephalon Present Regionally restricted 1D Expression is present in the rostral forebrain (the prospective olfactory bulb).
Specimen 1E: embryonic day 10.5 (more )
Note: This is a lateral view.
Structure Level Pattern Image Note
TS17: forelimb bud Present 1E
TS17: hindlimb bud Present 1E
TS17: hindbrain Present Regionally restricted 1E Expression is present in the midbrain-hindbrain border.
TS17: midbrain Present Regionally restricted 1E Expression is present in the midbrain-hindbrain border.
TS17: telencephalon Present Regionally restricted 1E Expression is present in the rostral forebrain (the prospective olfactory bulb).
TS17: 1st branchial arch Present 1E Expression is restricted from what was seen earlier in development.
Specimen 1F: embryonic day 11.5 (more )
Note: This is a lateral view.
Structure Level Pattern Image Note
TS19: forelimb bud Present 1F
TS19: hindlimb bud Present 1F
Specimen Not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: tail Absent Although expression was present in it earlier, expression is undetectable in the tail at this age.
TS17: nasal pit Present
Specimen 2A: embryonic day 8.0 (more )
Note: This is a parasagittal section.
Structure Level Pattern Image Note
TS12: embryo endoderm Present 2A Expression is present in the definitive endoderm.
TS12: primitive streak Present 2A Expression is present in the cells around and in the streak itself.
TS12: embryo mesenchyme Absent 2A There is no expression in newly-formed mesodermal cells.
Specimen 2B: embryonic day 9.5 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component ectoderm Present 2B
TS15: 1st branchial arch maxillary component ectoderm Present 2B
Specimen 3A: embryonic day 9.5 (more )
Note: This is a parasagittal section.
Structure Level Pattern Image Note
TS15: forelimb bud ectoderm Present 3A The expression zone is broad and intense.
Specimen 3B: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: hindlimb bud ectoderm Present 3B The expression zone is broad and intense.
Specimen 3C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present 3C
Specimen 3D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 3D
Specimen 3E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb Present 3E
Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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