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Arhgap23 Gene Detail
Summary
  • Symbol
    Arhgap23
  • Name
    Rho GTPase activating protein 23
  • Feature Type
    protein coding gene
  • IDs
    MGI:3697726
    NCBI Gene: 58996
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97306359-97393228 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 60.97 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2088 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3697726
 protein coding gene Chr11:97295183-97393228 (+)
129S1/SvImJ ENSMUSGG00200054990
 protein coding gene Chr11:94589872-94629410 (+)
A/J ENSMUSGG00195055524
 protein coding gene Chr11:94312022-94352068 (+)
AKR/J ENSMUSGG00220054944
 protein coding gene Chr11:94571153-94611200 (+)
BALB/cJ ENSMUSGG00180055636
 protein coding gene Chr11:94576742-94616782 (+)
C3H/HeJ ENSMUSGG00175055187
 protein coding gene Chr11:94569916-94609452 (+)
C57BL/6NJ ENSMUSGG00215055830
 protein coding gene Chr11:94160770-94200312 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017055
 protein coding gene Chr11:93191482-93279492 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210055137
 protein coding gene Chr11:94274141-94314176 (+)
DBA/2J ENSMUSGG00185057986
 protein coding gene Chr11:94619804-94659340 (+)
FVB/NJ ENSMUSGG00205054702
 protein coding gene Chr11:94478984-94519048 (+)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055921
 protein coding gene Chr11:95672819-95712355 (+)
NOD/ShiLtJ ENSMUSGG00190055131
 protein coding gene Chr11:94662697-94702206 (+)
NZO/HlLtJ ENSMUSGG00225055718
 protein coding gene Chr11:97725383-97765428 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ARHGAP23, Rho GTPase activating protein 23
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGAP23, Rho GTPase activating protein 23
  • Links
    NCBI Gene ID: 57636
    UniProt: Q9P227

  • Chr Location
    17q12; chr17:38419275-38512385 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    644
  • Tissues
    31
  • cDNA Data
    40
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000049807 Ensembl Gene Model | MGI Sequence Detail 86870 C57BL/6J ±  kb
    transcript ENSMUST00000121799 Ensembl | MGI Sequence Detail 5816 Not Applicable  
    polypeptide ENSMUSP00000112999 Ensembl | MGI Sequence Detail 1488 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 42
      cDNA 40
      Primer pair 2

      Microarray probesets 6
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 21
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory