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Gene Expression Data
Assay Details
Assay
Reference: J:95649 Kawakami Y, et al., Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos. Development. 2004 Oct;131(19):4763-74
Assay type: RNA in situ
MGI Accession ID: MGI:3689360
Gene symbol: Sp8
Gene name: trans-acting transcription factor 8
Probe: Sp8 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 2N: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: neural tube Present 2N
TS14: prosencephalon Present 2N
TS14: future hindbrain Present Regionally restricted 2N Expression is at the midbrain/hindbrain boundary.
TS14: future midbrain Present Regionally restricted 2N Expression is at the midbrain/hindbrain boundary.
Specimen 2O: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present 2O
TS15: neural tube Present 2O
TS15: future hindbrain Present Regionally restricted 2O Expression is at the midbrain/hindbrain boundary.
TS15: future midbrain Present Regionally restricted 2O Expression is at the midbrain/hindbrain boundary.
Specimen 2P: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud ectoderm Present Regionally restricted 2P Expression is in the ventral ectoderm.
Specimen 2Q: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud ectoderm Present Regionally restricted 2Q Expression is in the ventral ectoderm.
Specimen 2R: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong 2R
Specimen 5A wt: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present 5A
Specimen 6E wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present 6E
Specimen 6F Lrp6-/-: embryonic day 10.5; Lrp6Gt(Ex187)Byg/Lrp6Gt(Ex187)Byg (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Weak 6F In addition to weak expression, the domain of was shorter when compared with that of the wild-type limb.
Specimen 6G wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted 6G Expression is in the AER.
Specimen 6H Dkk-/-: embryonic day 12.5; Dkk1tm1Lmgd/Dkk1tm1Lmgd (more )
Structure Level Pattern Image Note
TS20: limb epithelium Strong Regionally restricted 6H The expression is in the AER and is ectopically induced outside the AER.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory