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Krtap4-22 Gene Detail
Summary
  • Symbol
    Krtap4-22
  • Name
    keratin associated protein 4-22
  • Synonyms
    Gm11595
  • Feature Type
    protein coding gene
  • IDs
    MGI:3652308
    NCBI Gene: 100040276
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99662540-99663739 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.12 cM
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3652308
 protein coding gene Chr11:99662540-99663739 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019114
 protein coding gene Chr11:102467597-102468791 (-)
A/J MGP_AJ_G0019084
 protein coding gene Chr11:98145997-98147341 (-)
AKR/J MGP_AKRJ_G0019054
 protein coding gene Chr11:101183909-101184650 (-)
BALB/cJ MGP_BALBcJ_G0019056
 protein coding gene Chr11:98674260-98676044 (-)
C3H/HeJ MGP_C3HHeJ_G0018870
 protein coding gene Chr11:101354918-101365052 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019506
 protein coding gene Chr11:105604555-105605359 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017138
 protein coding gene Chr11:95666039-95677830 (-)
CAST/EiJ MGP_CASTEiJ_G0018424
 protein coding gene Chr11:102375694-102377168 (-)
CBA/J MGP_CBAJ_G0018843
 protein coding gene Chr11:110012679-110021713 (-)
DBA/2J MGP_DBA2J_G0018949
 protein coding gene Chr11:97725523-97726767 (-)
FVB/NJ MGP_FVBNJ_G0018940
 protein coding gene Chr11:97218834-97220738 (-)
LP/J MGP_LPJ_G0019020
 protein coding gene Chr11:102980860-102988564 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018967
 protein coding gene Chr11:109663166-109664270 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0018192
 protein coding gene Chr11:98793730-98795674 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017980
 protein coding gene Chr11:101266631-101268795 (-)
WSB/EiJ MGP_WSBEiJ_G0018475
 protein coding gene Chr11:101525405-101526602 (-)



Homology
more
  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Synonyms
    KAP4.3
  • Links
    NCBI Gene ID: 85290
    neXtProt AC: NX_Q9BYR4
    UniProt: Q9BYR4

  • Chr Location
    17q21.2; chr17:41167231-41168221 (-)  GRCh38
  • Human Ortholog
    KRTAP4-9, keratin associated protein 4-9
  • Synonyms
    KAP4.9
  • Links
    NCBI Gene ID: 100132386
    neXtProt AC: NX_Q9BYQ8
    UniProt: Q9BYQ8

  • Chr Location
    17q21.2; chr17:41105389-41106488 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100040276 NCBI Gene Model | MGI Sequence Detail 1200 C57BL/6J ±  kb
transcript NM_001126322 RefSeq | MGI Sequence Detail 1200 C57BL/6  
polypeptide NP_001119794 RefSeq | MGI Sequence Detail 289 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
References
more
  • Summaries
    All 14
    Phenotypes 6
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory