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Krtap4-16 Gene Detail
Summary
  • Symbol
    Krtap4-16
  • Name
    keratin associated protein 4-16
  • Synonyms
    OTTMUSG00000002196
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651030
    NCBI Gene: 435285
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99741481-99742431 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.19 cM
Strain
Comparison
more
  • SNPs within 2kb
    104 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651030
 protein coding gene Chr11:99741481-99742434 (-)
129S1/SvImJ ENSMUSG00200051243
 protein coding gene Chr11:97005123-97006076 (-)
A/J ENSMUSG00195047938
 protein coding gene Chr11:96693920-96694873 (-)
AKR/J ENSMUSG00220049090
 protein coding gene Chr11:96954142-96955095 (-)
BALB/cJ ENSMUSG00180044899
 protein coding gene Chr11:97076281-97077235 (-)
C3H/HeJ ENSMUSG00175050640
 protein coding gene Chr11:96978668-96979621 (-)
C57BL/6NJ ENSMUSG00215052707
 protein coding gene Chr11:96560398-96561351 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017143
 protein coding gene Chr11:95724782-95725627 (-)
CAST/EiJ ENSTCUG00005048399
 protein coding gene Chr11:96482957-96483853 (-)
CBA/J ENSMUSG00210051701
 protein coding gene Chr11:96709632-96710586 (-)
DBA/2J ENSMUSG00185051302
 protein coding gene Chr11:97028542-97029495 (-)
FVB/NJ ENSMUSG00205028486
 protein coding gene Chr11:96888880-96889833 (-)
JF1/MsJ ENSUMUG00000045971
 protein coding gene Chr11:97295776-97296730 (-)
LP/J ENSMUSG00230050772
 protein coding gene Chr11:98081339-98082292 (-)
NOD/ShiLtJ ENSMUSG00190039371
 protein coding gene Chr11:97063416-97064369 (-)
NZO/HlLtJ ENSMUSG00225050137
 protein coding gene Chr11:100126204-100127157 (-)
PWK/PhJ ENSLUMG00010049847
 protein coding gene Chr11:96853282-96854236 (-)
SPRET/EiJ ENSMSPG00010047832
 protein coding gene Chr11:97339339-97340235 (-)
WSB/EiJ ENSIUOG00005047204
 protein coding gene Chr11:96841266-96842219 (-)



Homology
more
  • Human Ortholog
    KRTAP4-1, keratin associated protein 4-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP4-1, keratin associated protein 4-1
  • Synonyms
    KAP4.1, KAP4.10, KRTAP4-10, KRTAP4.10
  • Links
    NCBI Gene ID: 85285
    UniProt: Q9BYQ7

  • Chr Location
    17q21.2; chr17:41184100-41184911 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    4
  • Endonuclease-mediated
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Krtap4-16
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    8 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 435285 NCBI Gene Model | MGI Sequence Detail 951 C57BL/6J ±  kb
transcript NM_001013823 RefSeq | MGI Sequence Detail 972 FVB/N  
polypeptide NP_001013845 RefSeq | MGI Sequence Detail 202 FVB/N  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR002494 Keratin-associated protein
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:357457 Kumar V, et al., Keratin-dependent thymic stromal lymphopoietin expression suggests a link between skin blistering and atopic disease. J Allergy Clin Immunol. 2016;138(5):1461-1464
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory