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Arhgap40 Gene Detail
Summary
  • Symbol
    Arhgap40
  • Name
    Rho GTPase activating protein 40
  • Synonyms
    Gm14203
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649852
    NCBI Gene: 545481
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:158354716-158392682 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 78.72 cM
Strain
Comparison
more
  • SNPs within 2kb
    341 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649852
 protein coding gene Chr2:158354682-158392786 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026796
 protein coding gene Chr2:163590208-163628085 (+)
A/J MGP_AJ_G0026762
 protein coding gene Chr2:157027899-157067684 (+)
AKR/J MGP_AKRJ_G0026733
 protein coding gene Chr2:161654926-161693984 (+)
BALB/cJ MGP_BALBcJ_G0026771
 protein coding gene Chr2:157333024-157372293 (+)
C3H/HeJ MGP_C3HHeJ_G0026513
 protein coding gene Chr2:162003543-162042690 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027220
 protein coding gene Chr2:168471615-168509893 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024590
 protein coding gene Chr2:150468665-150507836 (+)
CAST/EiJ MGP_CASTEiJ_G0025975
 protein coding gene Chr2:162348713-162387148 (+)
CBA/J MGP_CBAJ_G0026490
 protein coding gene Chr2:174499574-174539897 (+)
DBA/2J MGP_DBA2J_G0026628
 protein coding gene Chr2:156203629-156241908 (+)
FVB/NJ MGP_FVBNJ_G0026595
 protein coding gene Chr2:154618055-154657399 (+)
LP/J MGP_LPJ_G0026731
 protein coding gene Chr2:163681005-163723004 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026616
 protein coding gene Chr2:178291699-178331402 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027276
 protein coding gene Chr2:161485036-161525569 (+)
PWK/PhJ MGP_PWKPhJ_G0025709
 protein coding gene Chr2:155739256-155779371 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025512
 protein coding gene Chr2:160408426-160449967 (+)
WSB/EiJ MGP_WSBEiJ_G0026045
 protein coding gene Chr2:162379338-162421407 (+)



Homology
more
  • Human Ortholog
    ARHGAP40, Rho GTPase activating protein 40
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGAP40, Rho GTPase activating protein 40
  • Synonyms
    C20orf95, dJ1100H13.4
  • Links
    NCBI Gene ID: 343578
    UniProt: Q5TG30

  • Chr Location
    20q11.23; chr20:38601809-38651035 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074625 Ensembl Gene Model | MGI Sequence Detail 37967 C57BL/6J ±  kb
transcript ENSMUST00000099133 Ensembl | MGI Sequence Detail 2162 Not Applicable  
polypeptide ENSMUSP00000096736 Ensembl | MGI Sequence Detail 672 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory