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Faiml Gene Detail
Summary
  • Symbol
    Faiml
  • Name
    Fas apoptotic inhibitory molecule like
  • Synonyms
    Gm6432
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647754
    NCBI Gene: 623459
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:99111429-99119292 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 51.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    86 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647754
 protein coding gene Chr9:99111429-99119292 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035166
 protein coding gene Chr9:100597530-100606744 (-)
A/J MGP_AJ_G0035147
 protein coding gene Chr9:97040472-97048416 (-)
AKR/J MGP_AKRJ_G0035079
 protein coding gene Chr9:99417163-99425022 (-)
BALB/cJ MGP_BALBcJ_G0035140
 protein coding gene Chr9:96723087-96730905 (-)
C3H/HeJ MGP_C3HHeJ_G0034850
 protein coding gene Chr9:99805223-99813057 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035660
 protein coding gene Chr9:103480823-103488660 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032559
 protein coding gene Chr9:94785852-94793899 (-)
CAST/EiJ MGP_CASTEiJ_G0034161
 protein coding gene Chr9:99618366-99626173 (-)
CBA/J MGP_CBAJ_G0034818
 protein coding gene Chr9:107016347-107024195 (-)
DBA/2J MGP_DBA2J_G0034980
 protein coding gene Chr9:96557032-96565262 (-)
FVB/NJ MGP_FVBNJ_G0034928
 protein coding gene Chr9:95374581-95382377 (-)
LP/J MGP_LPJ_G0035056
 protein coding gene Chr9:100843203-100852980 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034967
 protein coding gene Chr9:108948123-108955938 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035682
 protein coding gene Chr9:99656009-99667025 (-)
PWK/PhJ MGP_PWKPhJ_G0033868
 protein coding gene Chr9:96772037-96780326 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033703
 protein coding gene Chr9:99724774-99738500 (-)
WSB/EiJ MGP_WSBEiJ_G0034281
 protein coding gene Chr9:99529763-99537554 (-)



Homology
more
  • Human Ortholog
    FAIM, Fas apoptotic inhibitory molecule
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAIM, Fas apoptotic inhibitory molecule
  • Synonyms
    FAIM1
  • Links
    NCBI Gene ID: 55179
    neXtProt AC: NX_Q9NVQ4
    UniProt: Q9NVQ4

  • Chr Location
    3q22.3; chr3:138608606-138633376 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit slightly reduced testis size.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    10
  • cDNA Data
    1
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 623459 NCBI Gene Model | MGI Sequence Detail 7864 C57BL/6J ±  kb
    transcript NM_001244762 RefSeq | MGI Sequence Detail 785 C57BL/6  
    polypeptide NP_001231691 RefSeq | MGI Sequence Detail 178 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR038513 FAIM1 domain superfamily
      IPR010695 Fas apoptotic inhibitory molecule 1
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 1
      Primer pair 1
    References
    more
    • Summaries
      All 13
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 3
    • Earliest
      J:218517 Qiu H, et al., Lineage-specific duplications of Muroidea Faim and Spag6 genes and atypical accelerated evolution of the parental Spag6 gene. J Mol Evol. 2013 Sep;77(3):119-29
    • Latest
      J:308859 Akter MS, et al., CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice. Sci Rep. 2021 Jul 29;11(1):15438
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory